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7-ethyl-10-hydroxycamptothecin
Known as:
7-Ethyl-10-hydroxy-20(S)-camptothecin
National Institutes of Health
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Related topics
Related topics
2 relations
Narrower (1)
SN 38
irinotecan
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
THE DEVELOPMENT AND VALIDATION OF A CHIRAL HIGH PERFORMANCE LIQUID CHROMATOGRAPHY METHOD FOR THE IDENTIFICATION AND QUANTIFICATION OF ( R )-ENANTIOMER IN 7-ETHYL-10-HYDROXYCAMPTOTHECIN ( SN-38 )
A. Venkateshwarlu
,
A. Rao
,
K. Mukkanti
,
S. Reddy
2014
Corpus ID: 51783542
Objective: The objective of the method was to develop a new and simple, rapid, isocratic, normal phase chiral HPLC method for the…
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2014
2014
7-ethyl-10-hydroxycamptothecin prodrugs and their preparation and use
王杭祥
2014
Corpus ID: 145856808
本发明公开了7‑乙基‑10‑羟基喜树碱药物前体及其制备方法和应用。 该药物前体的结构式如式(Ⅰ)或式(Ⅱ)所示，是由7‑乙基‑10‑羟基喜树碱的C‑10位或C‑20…
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2013
2013
Premature Senescence Program Linked to Apoptosis and ( PRC )-dependent Inflammatory Stress Activation of a PGC-1-related Coactivator Gene Regulation :
Natalie Gleyzer
,
R. Scarpulla
2013
Corpus ID: 207857029
2010
2010
Method of inhibiting angiogenesis using multi-arm polymer conjugates of 7-ethyl-10-hydroxycamptothecin
サプラ，プージャ
,
パストリーノ，ファビオ
,
ポンツォーニ，ミルコ
2010
Corpus ID: 102915217
The present invention relates to a method of inhibiting angiogenesis in a mammal. The present invention, to a mammal in need…
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2010
2010
Methods for inhibiting angiogenesis with multi-arm polymeric conjugates of 7-ethyl-10-hydroxycamptothecin
푸자 사프라
,
파비오 파스토리노
,
미르코 폰조니
2010
Corpus ID: 140243999
본 발명은 포유동물에서 신생혈관형성 억제 방법과 관련된다. 본 발명은 7-에틸-10-하이드록시캄토테신의 고분자 프로드러그를 그것이 필요한 포유동물에 투여하는 단계를 포함한다. 또한, 본 발명은 7-에틸-10…
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2010
2010
Method of treating her2 positive cancer with her2 receptor antagonist in combination with multi-arm polymeric conjugates of 7-ethyl-10-hydroxycamptothecin
푸자 사프라
2010
Corpus ID: 140322551
본 발명은 포유류에서 HER2 양성암을 치료하는 방법에 관한 것이다. 본 발명은 포유류에 상기의 필요에 따라 HER2 길항제를 7-에틸-10-히드록시캠토테신의 중합 전구약물과 병용하여 투여하는 것을 포함한다.
2010
2010
Role of Rad 51 Down-Regulation and Extracellular Signal-Regulated Kinases 1 and 2 Inactivation in Emodin and Mitomycin C-Induced Synergistic Cytotoxicity in Human Non – Small-Cell Lung Cancer Cells
Ying Su
,
M. Tsai
,
+4 authors
Yun-Wei Lin
2010
Corpus ID: 27498528
Emodin (1,3,8-trihydroxy-6-methyl-anthraquinone) is a natural anthraquinone derivative found in the roots and rhizomes of…
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2008
2008
A phase I dose-escalation study of NK012
H. Burris
,
J. Infante
,
+5 authors
S. Jones
2008
Corpus ID: 56803084
2538 Background: NK012 is a micelle-forming macromolecular prodrug of EHC (7-ethyl-10-hydroxycamptothecin), also known as SN-38…
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2007
2007
Marked antitumor activity of NK012, 7-ethyl-10-hydroxycamptothecin-incorporating micellar nanoparticle, in liver metastatic tumor model of colorectal cancer
Takeshi Onda
,
E. Ichimura
,
S. Matsumoto
,
K. Okamoto
,
K. Nishikawa
2007
Corpus ID: 80342824
1495 Background : NK012 is a micellar-forming nanoparticle of 7-ethyl-10-hydroxycamptothecin (EHC or SN-38), an active metabolite…
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2007
2007
Breast cancer, colorectal cancer, pancreatic cancer, multi-arm polymer conjugates of 7-ethyl-10-hydroxycamptothecin for treatment of ovarian cancer and lung cancer
ウ，デチュン
,
ザオ，ホン
,
サプラ，プジャ
,
ベレン ルビオ，マリア
2007
Corpus ID: 80131606
For example, the structural formula: [Formula 1] In represented, 4 arms - discloses polyethylene glycol-7-ethyl-10…
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