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7-dehydropregnenolone

 
National Institutes of Health

Papers overview

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Review
2020
Review
2020
We have previously described new pathways of vitamin D3 activation by CYP11A1 to produce a variety of metabolites including 20(OH… Expand
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2015
2015
BackgroundCholesterol, the precursor of all steroid hormones, is the most abundant steroid in vertebrates and exhibits highly… Expand
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Review
2013
Review
2013
Novel metabolic pathways initiated by the enzymatic action of CYP11A1 on 7DHC (7-dehydrocholesterol), ergosterol, vitamins D3 and… Expand
2013
2013
CYP17 (steroid 17α-hydroxylase/17,20-lyase) is a key enzyme in steroid hormone biosynthesis. It catalyzes two independent… Expand
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Highly Cited
2012
Highly Cited
2012
The discovery that 7-dehydrocholesterol (7DHC) is an excellent substrate for cytochrome P450scc (CYP11A1) opens up new… Expand
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2011
2011
LETTER TO THE EDITOR The active form of vitamin D, 1,25(OH)2D3, has a number of desirable properties in addition to its… Expand
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Highly Cited
2010
Highly Cited
2010
Background Cytochrome P450scc metabolizes vitamin D3 to 20-hydroxyvitamin D3 (20(OH)D3) and 20,23(OH)2D3, as well as 1… Expand
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Highly Cited
2009
Highly Cited
2009
Since P450scc transforms 7-dehydrocholesterol (7DHC) to 7-dehydropregnenolone (7DHP) in vitro, we investigated sequential 7DHC… Expand
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Highly Cited
2004
Highly Cited
2004
Following up on our previous findings that the skin possesses steroidogenic activity from progesterone, we now show widespread… Expand
Highly Cited
2003
Highly Cited
2003
Metabolites of vitamin D3 (D3) (cholecalciferol) are recognized as enzymatically formed chemicals in humans that can influence a… Expand
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