7-aminoactinomycin D

Known as: 7AAD, 7-amino-actinomycin D, 7-ADD 
A fluorescent nucleic acid dye which selectively binds GC sequences in double-stranded DNA. It has a molecular weight of 1270.5, an absorbance… (More)
National Institutes of Health

Papers overview

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2012
2012
7-Aminoactinomycin D (7-AAD) is a DNA dye that distinguishes viable, apoptotic, and late apoptotic/dead cells in flow cytometry… (More)
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Highly Cited
2011
Highly Cited
2011
Inflammasomes are a family of cytosolic multiprotein complexes that initiate innate immune responses to pathogenic microbes by… (More)
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Highly Cited
2005
Highly Cited
2005
istic upmodulation of CD20 and downmodulation of CD10, comparable to the immunophenotypic modulation observed in vivo. In… (More)
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Highly Cited
2005
Highly Cited
2005
PURPOSE Regulatory T cells (T-reg) that control harmful autoimmune T cells in the periphery may also suppress the immune response… (More)
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Review
2002
Review
2002
Apoptosis and primary necrosis are the two modes of cell death induced by a lethal injury. The majority of structural and… (More)
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2002
2002
The resistance to Apo2 ligand (Apo2L)/tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis could be… (More)
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Highly Cited
1996
Highly Cited
1996
The detection and quantitation of apoptotic cells is becoming increasingly important in the investigation of the role of… (More)
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Highly Cited
1995
Highly Cited
1995
We present cell cycling and functional evidence that the CD34+CD38- immunophenotype can be used to define a rare and primitive… (More)
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Highly Cited
1992
Highly Cited
1992
Identification of nonviable cells in immunofluorescently stained cell populations is essential for obtaining accurate data… (More)
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1991
1991
The potent RNA polymerase inhibitors actinomycin D and 7-aminoactinomycin D are shown to bind to single-stranded DNAs. The… (More)
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