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National Institutes of Health
analogs & derivatives
Semantic Scholar uses AI to extract papers important to this topic.
Analysis of Cellular Factors assisting AGT Regulation
Corpus ID: 41205942
O 6 Methyguanine-DNA methyl transferase is a very critical enzyme in a cell. It protects cells from carcinogens and protects the…
TargetedModulation ofMGMT : Clinical Implications
Corpus ID: 6036477
O-MethylguanineDNAmethyltransferase (MGMT) has been studied for >20 years as a gene that is associatedwith themutagenicity and…
O 6-Methylguanine-DNAMethyltransferase , O 6-Benzylguanine , and Resistance to Clinical Alkylators in Pediatric Primary BrainTumor Cell Lines
J. R. Geyer
Corpus ID: 14599860
Purpose:Primarybraintumors are the leadingcauseofcancerdeathinchildren.Ourpurpose is (a) to assess the contribution of the DNA…
Evidence that covalent complex formation between BCNU-treated oligonucleotides and E. coli alkyltransferases requires the O6- alkylguanine function
P. E. Gonzaga
Nucleic Acids Res.
Corpus ID: 19817251
Chloroethylnitrosoureas (CENUs) are thought to induce cytotoxic DNA interstrand cross-links via an initial reaction at O6…
Formation of the cross-linked base, diguanylethane, in DNA treated with N,N'-bis(2-chloroethyl)-N-nitrosourea.
Corpus ID: 44598476
A cross-linked base, diguanylethane, has been isolated and identified as a product of the reaction of N,N'-bis(2-chloroethyl)-N…
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