6-methyl-2-(phenylethynyl)pyridine

 
National Institutes of Health

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Highly Cited
2010
Highly Cited
2010
Synaptic modifications in the nucleus accumbens (NAc) are important for adaptive and pathological reward-dependent learning… (More)
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Highly Cited
2007
Highly Cited
2007
 
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Highly Cited
2004
Highly Cited
2004
Glutamatergic neurotransmission plays a critical role in addictive behaviors, and recent evidence indicates that genetic or… (More)
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Highly Cited
2004
Highly Cited
2004
Previous reports have demonstrated the anxiolytic effect of the potent and systemically active metabotropic glutamate subtype 5… (More)
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Highly Cited
2004
Highly Cited
2004
Growing evidence suggests a role for metabotropic glutamate receptors (mGluRs) in the behavioral effects of cocaine related to… (More)
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Highly Cited
2003
Highly Cited
2003
2-Methyl-6-(phenylethynyl)pyridine (3), a potent noncompetitive mGlu5 receptor antagonist widely used to characterize the… (More)
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2003
2003
In rats with chronic constriction of one sciatic nerve (CCI rats), showing behavioural signs of neuropathic pain, 6-methyl-2… (More)
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Highly Cited
2000
Highly Cited
2000
Recently, selective and systemically active antagonists for the metabotropic glutamate 5 receptor (mGlu(5)) were discovered, and… (More)
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Highly Cited
2000
Highly Cited
2000
We have investigated the mechanism of inhibition and site of action of the novel human metabotropic glutamate receptor 5 (hmGluR5… (More)
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Highly Cited
1999
Highly Cited
1999
In the present paper we describe 2-methyl-6-(phenylethynyl)-pyridine (MPEP) as a potent, selective and systemically active… (More)
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