6-hydroxy-5-methoxy-2-indolylcarboxylic acid

Normal and malignant melanocytes produce melanins and melanin-related metabolites, most of which are retained in the cells but… Expand

Melanin is usually produced in melanocytes; however, our histologic research indicates that brownish black persistent… Expand

In a series of 92 patients with malignant melanoma, clinical stage III or IV, both 5-S-cysteinyldopa (5SCD) and 6-hydroxy-5… Expand

Generalized melanosis occurs very rarely as a complication of malignant melanoma, and the pathogenesis of this condition is still… Expand

Elevated levels of the phaeomelanin metabolite 5-S-cysteinyldopa and the eumelanin metabolite 6-hydroxy-5- methoxyindole-2… Expand

Serum concentrations of 5-S-cysteinyldopa (5-S-CD) and 6-hydroxy-5-methoxyindole-2-carboxylic acid (6H5MI2C) have been used as… Expand

Melanin synthesis is a biologic property unique to the melanocyte. It is highly elevated in malignant melanoma with the… Expand

The urinary excretion of the pheomelanin precursor 5− S-cysteinyldopa (5-S-CD) has been used as a tumour marker for metastatic… Expand

5,6-Dihydroxyindole (5,6DHI) and 5,6-dihydroxyindole-2-carboxylic acid (5,6DHI2C) are ultimate precursors of the black melanin… Expand

Urinary excretion of the phaeomelanin precursor 5-S-cysteinyldopa (5-S-CD) and the eumelanin metabolite 6-hydroxy-5-methoxyindole… Expand