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6-hydroxy-5-methoxy-2-indolylcarboxylic acid

Known as: 6H5MI2C, 6-hydroxy-5-methoxyindole-2-carboxylic acid, 5-methoxy-6-hydroxyindole-2-carboxylic acid 
 
National Institutes of Health

Papers overview

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2006
2006
Normal and malignant melanocytes produce melanins and melanin-related metabolites, most of which are retained in the cells but… Expand
Highly Cited
2004
Highly Cited
2004
  • K. Maeda, M. Hatao
  • The Journal of investigative dermatology
  • 2004
  • Corpus ID: 25972976
Melanin is usually produced in melanocytes; however, our histologic research indicates that brownish black persistent… Expand
2000
2000
In a series of 92 patients with malignant melanoma, clinical stage III or IV, both 5-S-cysteinyldopa (5SCD) and 6-hydroxy-5… Expand
1998
1998
Generalized melanosis occurs very rarely as a complication of malignant melanoma, and the pathogenesis of this condition is still… Expand
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Highly Cited
1997
Highly Cited
1997
Elevated levels of the phaeomelanin metabolite 5-S-cysteinyldopa and the eumelanin metabolite 6-hydroxy-5- methoxyindole-2… Expand
1995
1995
Serum concentrations of 5-S-cysteinyldopa (5-S-CD) and 6-hydroxy-5-methoxyindole-2-carboxylic acid (6H5MI2C) have been used as… Expand
1994
1994
Melanin synthesis is a biologic property unique to the melanocyte. It is highly elevated in malignant melanoma with the… Expand
1991
1991
The urinary excretion of the pheomelanin precursor 5− S-cysteinyldopa (5-S-CD) has been used as a tumour marker for metastatic… Expand
Highly Cited
1988
Highly Cited
1988
5,6-Dihydroxyindole (5,6DHI) and 5,6-dihydroxyindole-2-carboxylic acid (5,6DHI2C) are ultimate precursors of the black melanin… Expand
1985
1985
Urinary excretion of the phaeomelanin precursor 5-S-cysteinyldopa (5-S-CD) and the eumelanin metabolite 6-hydroxy-5-methoxyindole… Expand