6-hydroxy-5-methoxy-2-indolylcarboxylic acid

Normal and malignant melanocytes produce melanins and melanin-related metabolites, most of which are retained in the cells but… (More)

Melanin is usually produced in melanocytes; however, our histologic research indicates that brownish black persistent… (More)

In a series of 92 patients with malignant melanoma, clinical stage III or IV, both 5-S-cysteinyldopa (5SCD) and 6-hydroxy-5… (More)

Generalized melanosis occurs very rarely as a complication of malignant melanoma, and the pathogenesis of this condition is still… (More)

Elevated levels of the phaeomelanin metabolite 5-S-cysteinyldopa and the eumelanin metabolite 6-hydroxy-5-methoxyindole-2… (More)

Serum concentrations of 5-S-cysteinyldopa (5-S-CD) and 6-hydroxy-5-methoxyindole-2-carboxylic acid (6H5MI2C) have been used as… (More)

Melanin synthesis is a biologic property unique to the melanocyte. It is highly elevated in malignant melanoma with the… (More)

Two eu-melanin precursors, 6-hydroxy-5-methoxyindole-2-carboxylic acid (HMI2C) and 5,6-dihydroxyindole-2-carboxylic acid (DHI2C… (More)

The urinary excretion of the pheomelanin precursor 5-S-cysteinyldopa (5-S-CD) has been used as a tumour marker for metastatic… (More)

5,6-Dihydroxyindole (5,6DHI) and 5,6-dihydroxyindole-2-carboxylic acid (5,6DHI2C) are ultimate precursors of the black melanin… (More)