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6-hydroxy-5-methoxy-2-indolylcarboxylic acid

Known as: 6H5MI2C, 6-hydroxy-5-methoxyindole-2-carboxylic acid, 5-methoxy-6-hydroxyindole-2-carboxylic acid 
National Institutes of Health

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5-hydroxy-6-methoxy-2-indolylcarboxylic acid

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Papers overview

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2006
2006
Evaluation of melanin-related metabolites as markers of solar ultraviolet-B radiation.
Ultraviolet-B (UVB) radiation due sunlight can result in sunburns and/or suntans. Sunburn occurs only several hours after solar… 
Highly Cited
2004
Highly Cited
2004
Involvement of photooxidation of melanogenic precursors in prolonged pigmentation induced by ultraviolet A.
Melanin is usually produced in melanocytes; however, our histologic research indicates that brownish black persistent… 
2000
2000
The value of cysteinyldopa in the follow-up of disseminated malignant melanoma
In a series of 92 patients with malignant melanoma, clinical stage III or IV, both 5-S-cysteinyldopa (5SCD) and 6-hydroxy-5… 
1998
1998
Generalized Melanosis in Metastatic Malignant Melanoma: The Possible Role of DOPAquinone Metabolites
Generalized melanosis occurs very rarely as a complication of malignant melanoma, and the pathogenesis of this condition is still… 
Highly Cited
1997
Highly Cited
1997
S100B protein, 5-S-cysteinyldopa and 6-hydroxy-5- methoxyindole-2-carboxylic acid as biochemical markers for survival prognosis in patients with malignant melanoma
Elevated levels of the phaeomelanin metabolite 5-S-cysteinyldopa and the eumelanin metabolite 6-hydroxy-5- methoxyindole-2… 
1994
1994
High plasma level of a eumelanin precursor, 6-hydroxy-5-methoxyindole-2-carboxylic acid as a prognostic marker for malignant melanoma.
Melanin synthesis is a biologic property unique to the melanocyte. It is highly elevated in malignant melanoma with the… 
1994
1994
The mouse brown (b) locus protein functions as a dopachrome tautomerase.
The mouse b locus controls black/brown coat coloration. Its product, the b-protein or TRP-1, has significant homology to… 
1991
1991
Normal values of urinary excretion and serum concentration of 5‐S‐cysteinyldopa and 6‐hydroxy‐ 5‐methoxyindole‐2‐carboxylic acid, biochemical markers of melanoma progression
The urinary excretion of the pheomelanin precursor 5− S-cysteinyldopa (5-S-CD) has been used as a tumour marker for metastatic… 
Highly Cited
1988
Highly Cited
1988
Preparation of eumelanin-related metabolites 5,6-dihydroxyindole, 5,6-dihydroxyindole-2-carboxylic acid, and their O-methyl derivatives.
1985
1985
Urinary excretion of 5-S-cysteinyldopa and 6-hydroxy-5-methoxyindole-2-carboxylic acid: differences between pigmented and albino mice.
Urinary excretion of the phaeomelanin precursor 5-S-cysteinyldopa (5-S-CD) and the eumelanin metabolite 6-hydroxy-5-methoxyindole… 
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