6'-guanidinonaltrindole

Known as: 6'-GNTI

National Institutes of Health

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2011

2011

6′‐Guanidinonaltrindole (6′‐GNTI) is a potent and functionally unique kappa opioid agonist that displays bias against beta‐arrestin recruitment and receptor internalization

J. StreicherChad E GroerThomas A. MunroCécile BéguinB. CohenL. Bohn
The FASEB Journal
2011
Corpus ID: 83270003

Functional selectivity is a phenomenon whereby different ligands activate distinct signaling cascades through the same receptor…