6',7'-dihydroxybergamottin

Known as: 6,7-DHB 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1996-2016
0519962016

Papers overview

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2012
2012
OBJECTIVES We previously established HepG2-GS-3A4, a cell line from hepatoblastoma with overexpression of human CYP3A4 and… (More)
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2004
2004
OBJECTIVE Our objective was to assess the contribution of 6',7'-dihydroxybergamottin (DHB) to the inhibitory effect of grapefruit… (More)
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2004
2004
Bergamottin (BG) and 6',7'-dihydroxybergamottin (DHB) are the most abundant furanocoumarins present in grapefruit juice and have… (More)
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Highly Cited
2004
Highly Cited
2004
OBJECTIVES Phytochemical-mediated modulation of cytochrome P450 (CYP) activity may underlie many herb-drug interactions. Single… (More)
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2001
2001
OBJECTIVE Our objective was to determine whether Seville orange juice produces a grapefruit juice-like interaction with… (More)
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2000
2000
OBJECTIVES To determine whether unprocessed grapefruit can cause a drug interaction, whether the active ingredients are naturally… (More)
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1999
1999
BACKGROUND 6',7'-Dihydroxybergamottin is a furanocoumarin that inhibits CYP3A4 and is found in grapefruit juice and Seville… (More)
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1998
1998
OBJECTIVE To test whether naringin or 6',7'-dihydroxybergamottin is a major active substance in grapefruit juice-felodipine… (More)
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Highly Cited
1997
Highly Cited
1997
Grapefruit juice increases the oral availability of a variety of CYP3A4 substrates. It has been shown that recurrent grapefruit… (More)
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1996
1996
Grapefruit juice inhibits the metabolism of substrates for enzymes of the CYP3A subfamily. However, the identity of the inhibitor… (More)
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