5-hydroxymethylcytosine

Known as: 4-amino-5-(hydroxymethyl)-2(1H)-pyrimidinone, 5-hydroxylmethylcytosine 
 
National Institutes of Health

Papers overview

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Review
2017
Review
2017
Ten-eleven translocation (TET) enzymes catalyze the oxidation of 5-methylcytosine (5-mC) to 5-hydroxymethylcytosine (5-hmC) and… (More)
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Highly Cited
2013
Highly Cited
2013
Mouse primordial germ cells (PGCs) undergo sequential epigenetic changes and genome-wide DNA demethylation to reset the epigenome… (More)
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Highly Cited
2011
Highly Cited
2011
5-hydroxymethylcytosine (5hmC) is a modified base present at low levels in diverse cell types in mammals. 5hmC is generated by… (More)
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Highly Cited
2011
Highly Cited
2011
Methylation at the 5′ position of cytosine in DNA has important roles in genome function and is dynamically reprogrammed during… (More)
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Highly Cited
2011
Highly Cited
2011
TET family enzymes convert 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC) in DNA. Here, we show that Tet1 and Tet2 are… (More)
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Highly Cited
2011
Highly Cited
2011
5-methylcytosine (5mC) in DNA plays an important role in gene expression, genomic imprinting, and suppression of transposable… (More)
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Review
2011
Review
2011
Just over 2 years ago, TET1 was found to catalyse the oxidation of 5-methylcytosine, a well-known epigenetic mark, into 5… (More)
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Highly Cited
2011
Highly Cited
2011
The epigenomes of early mammalian embryos are extensively reprogrammed to acquire a totipotent developmental potential. A major… (More)
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Highly Cited
2009
Highly Cited
2009
DNA cytosine methylation is crucial for retrotransposon silencing and mammalian development. In a computational search for… (More)
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Highly Cited
2009
Highly Cited
2009
Despite the importance of epigenetic regulation in neurological disorders, little is known about neuronal chromatin. Cerebellar… (More)
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