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5-hydroxyisourate

 
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
Significance Human susceptibility to gout is driven by the fact that we have a pseudogene for uricase that prevents a functional… Expand
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2011
2011
The high-resolution crystal structure of S. marcescens Lip reveals a new member of the transthyretin family of proteins. Lip, a… Expand
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Highly Cited
2011
Highly Cited
2011
Urate and myeloperoxidase (MPO) are associated with adverse outcomes in cardiovascular disease. In this study, we assessed… Expand
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2010
2010
With the notable exception of humans, uric acid is degraded to (S)-allantoin in a biochemical pathway catalyzed by urate oxidase… Expand
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2009
2009
The enterobacterium Klebsiella oxytoca uses a variety of inorganic and organic nitrogen sources, including purines, nitrogen-rich… Expand
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Highly Cited
2006
Highly Cited
2006
Mammals that degrade uric acid are not affected by gout or urate kidney stones. It is not fully understood how they convert uric… Expand
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2006
2006
The mechanism of binding of thyroid hormones by the transport protein transthyretin (TTR) in vertebrates is structurally well… Expand
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2006
2006
Uric acid is the end product of the purine degradation pathway in humans. It is catabolized to allantoin by urate oxidase or… Expand
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2005
2005
Purine catabolic pathway in Bacillus subtilis is consisted of more than 14 genes. Among these genes, pucL and pucM are required… Expand
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1999
1999
We report the identification and purification of a novel enzyme from soybean root nodules that catalyzes the hydrolysis of 5… Expand
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