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5-hydroxy-1-methylhydantoin

Known as: 5-hydroxy-1-methylimidazolidine-2,4-dione 
 
National Institutes of Health

Papers overview

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2020
2020
Paraquat (PQ) is a non-selective herbicide and is exceedingly toxic to humans. The mechanism of PQ toxicity is very complex and… Expand
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2018
2018
OBJECTIVE To investigate the effects of 5-hydroxy-1-methylhydantoin (HMH) on kidney injury induced by paraquat (PQ). METHODS… Expand
2015
2015
OBJECTIVE To investigate the protective effects of 5-hydroxy-1-methylhyantoin (HM ) on paraquat (PQ)-induced nephrotoxicity in… Expand
2014
2014
Abstract A creatinine metabolite, 5-hydroxy-1-methylhydantoin (HMH: NZ-419), a hydroxyl radical scavenger, has previously been… Expand
2013
2013
HMH (5-hydroxy-1-methylhydantoin; NZ-419) is a mammalian creatinine metabolite and an intrinsic antioxidant. HMH prevents the… Expand
2011
2011
Creatinine (Crn) is one of the main intrinsic hydroxyl radical (•OH) scavengers and an ideal one for healthy or normal mammals… Expand
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2011
2011
AIMS In mammals, creatinine (Cr) is catabolized by a dual oxidative pathway via 5-hydroxy-1-methylhydantoin or 5… Expand
2009
2009
The concentration of NZ-419 (5-hydroxy-1-methylimidazolidine-2,4-dione), an intrinsic antioxidant, has been shown to increase in… Expand
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2005
2005
Both 5-hydroxy-1-methylhydantoin (3) and the hitherto unrecognized 5-hydroxycreatinine (2-amino-5-hydroxy-1-methyl-imidazol-4(5H… Expand
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1988
1988
The metabolic pathway of 1-methylhydantoin (2) via 5-hydroxy-1-methylhydantoin (3), methylparabanic acid (4) and N5… Expand