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5-fluorouridine 5'-triphosphate
Known as:
FUTP
, uridine 5'-(tetrahydrogen triphosphate), 5-fluoro-
National Institutes of Health
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Related topics
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2 relations
Broader (1)
Uridine Triphosphate
analogs & derivatives
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
5-fluorouracil and cardiotoxicity: a review
J. Sara
,
J. Kaur
,
+6 authors
A. Grothey
Therapeutic Advances in Medical Oncology
2018
Corpus ID: 49569780
Fluoropyrimidines such as 5-fluorouracil (5-FU) form the foundation of a wide variety of chemotherapy regimens. 5-FU is in fact…
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Highly Cited
1996
Highly Cited
1996
Reduced Activity of Anabolizing Enzymes in 5‐Fluorouracil‐resistant Human Stomach Cancer Cells
M. Inaba
,
J. Mitsuhashi
,
+6 authors
M. Fukushima
Japanese journal of cancer research : Gann
1996
Corpus ID: 1785047
The mechanism of resistance to 5‐fluorouracil (5‐FU) was studied with NUGC‐3/5FU/L, a human stomach cancer cell line which had…
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Highly Cited
1995
Highly Cited
1995
Thymidine Phosphorylase Mediates the Sensitivity of Human Colon Carcinoma Cells to 5-Fluorouracil (*)
E. Schwartz
,
N. Baptiste
,
S. Wadler
,
D. Makower
Journal of Biological Chemistry
1995
Corpus ID: 2998862
Interferon-α (IFNα) potentiates the antitumor activity of 5-fluorouracil (FUra) in colon cancer in vitro, in vivo, and clinically…
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Review
1991
Review
1991
Biochemical pharmacology and analysis of fluoropyrimidines alone and in combination with modulators.
G. Weckbecker
Pharmacology and Therapeutics
1991
Corpus ID: 25360028
Review
1990
Review
1990
Metabolism and mechanism of action of 5-fluorouracil.
W. Parker
,
Yung‐chi Cheng
Pharmacology and Therapeutics
1990
Corpus ID: 45615253
Highly Cited
1989
Highly Cited
1989
Prediction of 5-fluorouracil cytotoxicity towards the Walker carcinosarcoma using peak integrals of fluoronucleotides measured by MRS in vivo.
Pmj McSheehy
,
Mjw Prior
,
JR Griffiths
British Journal of Cancer
1989
Corpus ID: 40348
19F-magnetic resonance spectroscopy (MRS) can be used to non-invasively monitor metabolism of 5-fluorouracil (5FU) to cytotoxic…
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Highly Cited
1988
Highly Cited
1988
5-Fluorouracil substitution alters pre-mRNA splicing in vitro.
S. Doong
,
B. Dolnick
Journal of Biological Chemistry
1988
Corpus ID: 24996653
Highly Cited
1981
Highly Cited
1981
Selective activation of 5'-deoxy-5-fluorouridine by tumor cells as a basis for an improved therapeutic index.
R. Armstrong
,
R. Diasio
Cancer Research
1981
Corpus ID: 25768583
The intracellular metabolism of a new fluoropyrimidine, 5'-deoxy-5-fluorouridine (5'-dFUrd), was compared with the metabolism of…
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Highly Cited
1980
Highly Cited
1980
Metabolism and biological activity of 5'-deoxy-5-fluorouridine, a novel fluoropyrimidine.
R. Armstrong
,
R. Diasio
Cancer Research
1980
Corpus ID: 37634214
5'-Deoxy-5-fluorouridine (5'-dFUrd; Roche 21-9738) is a recently synthesized antineoplastic agent with therapeutic potential. The…
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1980
1980
The effect of 5-fluorouridine 5'-triphosphate on RNA transcribed in isolated nuclei in vitro.
R. Glazer
,
M. Legraverend
Molecular Pharmacology
1980
Corpus ID: 42570536
Using nuclei prepared from rat liver, the effect of 5-fluorouridine 59-triphosphate (FUTP) was assessed on the nearest neighbor…
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