5-fluoromethylornithine
National Institutes of Health
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PURPOSE
To investigate the effect of amino acids on ornithine cytotoxicity in ornithine-delta-aminotransferase (OAT)-deficient…
Gyrate atrophy of the choroid and retina is a chorioretinal degeneration caused by hyperornithinemia and a deficiency of…
The protective effects of combinations of 5-fluoromethylornithine (5FMOrn), a selective inhibitor of ornithine aminotransferase…
Abstract5-Fluoromethylornithine (5FMOrn) is a selective inactivator of ornithine aminotransferase. Administration of this…
SummaryMice with the X-chromosomal sparse-fur (spf) mutation are an animal model of some hereditary deficiencies of ornithine…
Pretreatment of mice with 5-fluoromethylornithine (5FMOrn), a selective inactivator of ornithine aminotransferase, diminishes the…
The vertebrate brain has the machinery to transport arginine and ornithine, and to form within nerve endings from these amino…
5-Fluoromethylornithine (5FMOrn) is a selective inactivator of ornithine aminotransferase. Its administration causes a dramatic…