5-carboxylcytosine
National Institutes of Health
Papers overview
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DNA methylation (5-methylcytosine, 5mC) is involved in regulation of a wide range of biological processes. TET proteins can…
Transcription-activator-like effectors (TALEs) have been engineered to selectively recognize the epigenetic nucleobase 5…
Thymine DNA Glycosylase (TDG) is a base excision repair enzyme that acts as a thymine and uracil DNA N-glycosylase on G:T and G:U…
For several decades, 5-methylcytosine (5mC) has been thought to be the only DNA modification with a functional significance in…
Transcription-activator-like effector (TALE) proteins consist of concatenated repeats that recognize consecutive canonical…
MOTIVATION
5-methylcytosine (5mC) is a widely studied epigenetic modification of DNA. The ten-eleven translocation (TET…
Thymine DNA glycosylase (TDG) plays critical roles in DNA base excision repair and DNA demethylation. It has been proposed, based…
Epigenetic modification of the cytosine 5‐position is an important regulator of gene expression with essential roles in genome…
Oxidation of 5-methylcytosine has been proposed to mediate active and passive DNA demethylation. Tracking the history of DNA…