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5-carboxylcytosine

 
National Institutes of Health

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Highly Cited
2013
Highly Cited
2013
Tet proteins oxidize 5-methylcytosine (mC) to generate 5-hydroxymethyl (hmC), 5-formyl (fC), and 5-carboxylcytosine (caC). The… Expand
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Highly Cited
2013
Highly Cited
2013
TET dioxygenases successively oxidize 5-methylcytosine (5mC) in mammalian genomes to 5-hydroxymethylcytosine (5hmC), 5… Expand
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Highly Cited
2013
Highly Cited
2013
TET proteins oxidize 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC), and 5-carboxylcytosine… Expand
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Highly Cited
2012
Highly Cited
2012
Human thymine DNA glycosylase (hTDG) efficiently excises 5-carboxylcytosine (5caC), a key oxidation product of 5-methylcytosine… Expand
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Highly Cited
2011
Highly Cited
2011
Evidence for a possible route for DNA demethylation in animals is suggested. 5-methylcytosine (5mC) in DNA plays an important… Expand
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Highly Cited
2011
Highly Cited
2011
Evidence for a possible route for DNA demethylation in animals is suggested. The prevalent DNA modification in higher organisms… Expand
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Highly Cited
2011
Highly Cited
2011
Background: Thymine DNA glycosylase is essential for active DNA demethylation and embryonic development. Results: TDG rapidly… Expand
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Review
2011
Review
2011
Ten-eleven translocation 1-3 (Tet1-3) proteins have recently been discovered in mammalian cells to be members of a family of DNA… Expand
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Highly Cited
2011
Highly Cited
2011
Cellular development requires the silencing and activation of specific gene sequences in a well-orchestrated fashion… Expand
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Highly Cited
2010
Highly Cited
2010
5–Hydroxymethylcytosine (hmC) was recently detected as the sixth base in mammalian tissue at so far controversial levels. The… Expand
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