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5-benzylacyclouridine

Known as: 2,4(1H,3H)-Pyrimidinedione, 1-((2-hydroxyethoxy)methyl)-5-(phenylmethyl)- 
 
National Institutes of Health

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2006
2006
To aid in the clinical evaluation of zebularine, a potential oral antitumor agent, we initiated studies on the metabolism of… Expand
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1998
1998
Uridine phosphorylase (UPase) catalyzes the reversible phosphorolysis of uridine to uracil. We purified the enzyme from the… Expand
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1997
1997
A uridine phosphorylase inhibitor, 5-benzylacyclouridine (BAU), has been utilized as biochemical modulator of 5-fluorouracil (5… Expand
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1995
1995
The effects of subcutaneous administration of 5-benzylacyclouridine (BAU), a uridine phosphorylase (UrdPase, EC 2.4.2.3… Expand
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1993
1993
The pharmacokinetics and biochemical effects of the uridine phosphorylase (UrdPase) inhibitor 5-benzylacyclouridine (BAU) were… Expand
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1991
1991
The concentration of uridine (Urd) in murine tissues appears to be controlled by Urd catabolism, concentrative Urd transport, and… Expand
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1989
1989
SummaryInitial clinical trials have demonstrated that uridine (Urd) rescue given i.v. over at least 3 days can ameliorate 5… Expand
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1988
1988
The pharmacokinetics, tissue distribution and urinary excretion of the uridine (Urd) phosphorylase (EC 2.4.2.3) inhibitor 5… Expand
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1983
1983
5-Benzylacyclouridine (BAU) is a specific inhibitor of uridine phosphorylase, the first enzyme in the catabolism of uridine. It… Expand
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1982
1982
Various pyrimidine acyclonucleosides (1-(2'-hydroxyethoxymethyl)uracils) are specific inhibitors of uridine phosphorylase… Expand
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