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5-aminoisoquinolinone

Known as: 5-AIQ 
 
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
Poly(ADP-ribose)polymerase-1 is an important target enzyme in drug design; inhibitors have a wide variety of therapeutic… Expand
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2009
2009
Matrix metalloproteinase-2 (MMP-2), a ubiquitously expressed zinc-dependent endopeptidase, and poly(ADP-ribosyl) polymerase (PARP… Expand
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Review
2005
Review
2005
The poly(ADP-ribose)polymerases (PARPs) catalyse the transfer of ADP-ribose units from the substrate NAD(+) to acceptor proteins… Expand
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2004
2004
BACKGROUND Poly (ADP-ribose) polymerase (PARP), a nuclear enzyme activated by strand breaks in DNA, plays an important role in… Expand
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2004
2004
ObjectiveThe aim of this study was to investigate the impact of the novel, potent, water-soluble inhibitor of poly(adenosine… Expand
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2004
2004
Poly (ADP-ribose) polymerase (PARP), a nuclear enzyme activated by strand breaks in DNA, plays an important role in the colon… Expand
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2002
2002
BACKGROUND This study was designed to investigate the effects of 5-aminoisoquinolinone (5-AIQ), a water-soluble potent inhibitor… Expand
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2001
2001
This study investigates the effects of a novel, water-soluble inhibitor of the activity of poly (adenosine 5'-diphosphate ribose… Expand
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2001
2001
Poly (ADP-ribose) polymerase (PARP), a nuclear enzyme activated by strand breaks in DNA, plays an important role in the tissue… Expand
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Highly Cited
2000
Highly Cited
2000
Poly (ADP-ribose) synthetase (PARP) is a nuclear enzyme activated by strand breaks in DNA, which are caused inter alia by… Expand
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