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5-aminoisoquinolinone

Known as: 5-AIQ 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2000-2016
024620002016

Related topics

Related topics

1 relation

Broader (1)

Isoquinolines

Related mentions per year

Related mentions per year

1946-2018
19401960198020002020
5-aminoisoquinolinone
Isoquinolines

Papers overview

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2009
2009
Inhibition of matrix metalloproteinase-2 by PARP inhibitors.
Matrix metalloproteinase-2 (MMP-2), a ubiquitously expressed zinc-dependent endopeptidase, and poly(ADP-ribosyl) polymerase (PARP… (More)
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2007
2007
[Inhibitory effect of 5-aminoisoquinolinone on PARP activity in colon carcinoma cell line HT-29].
BACKGROUND & OBJECTIVE 5-Aminoisoquinolinone(5-AIQ),a poly(adenosine 5'-diphosphate ribose) polymerase (PARP) inhibitor, plays an… (More)
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2006
2006
Poly(ADP-ribose)polymerase inhibition decreases angiogenesis.
Inhibitors of poly(ADP-ribose)polymerase (PARP), a nuclear enzyme involved in regulating cell death and cellular responses to DNA… (More)
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2004
2004
5-Aminoisoquinolinone reduces renal injury and dysfunction caused by experimental ischemia/reperfusion.
BACKGROUND Poly (ADP-ribose) polymerase (PARP), a nuclear enzyme activated by strand breaks in DNA, plays an important role in… (More)
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2004
2004
5-Aminoisoquinolinone reduces colon injury by experimental colitis
Poly (ADP-ribose) polymerase (PARP), a nuclear enzyme activated by strand breaks in DNA, plays an important role in the colon… (More)
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2004
2004
5-Aminoisoquinolinone, a novel inhibitor of poly(adenosine disphosphate-ribose) polymerase, reduces microvascular liver injury but not mortality rate after hepatic ischemia-reperfusion.
OBJECTIVE The aim of this study was to investigate the impact of the novel, potent, water-soluble inhibitor of poly(adenosine… (More)
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2002
2002
The novel PARP inhibitor 5-aminoisoquinolinone reduces the liver injury caused by ischemia and reperfusion in the rat.
BACKGROUND This study was designed to investigate the effects of 5-aminoisoquinolinone (5-AIQ), a water-soluble potent inhibitor… (More)
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2002
2002
Effects of 5-aminoisoquinolinone, a water-soluble, potent inhibitor of the activity of poly (ADP-ribose) polymerase, in a rodent model of lung injury.
Poly (ADP-ribose) polymerase (PARP), a nuclear enzyme activated by strand breaks in DNA, plays an important role in the tissue… (More)
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2001
2001
5-aminoisoquinolinone, a potent inhibitor of poly (adenosine 5'-diphosphate ribose) polymerase, reduces myocardial infarct size.
This study investigates the effects of a novel, water-soluble inhibitor of the activity of poly (adenosine 5'-diphosphate ribose… (More)
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2000
2000
Effects of 5-aminoisoquinolinone, a water-soluble, potent inhibitor of the activity of poly (ADP-ribose) polymerase on the organ injury and dysfunction caused by haemorrhagic shock.
Poly (ADP-ribose) synthetase (PARP) is a nuclear enzyme activated by strand breaks in DNA, which are caused inter alia by… (More)
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