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5-aminoisoquinolinone

Known as: 5-AIQ 
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
Poly(ADP-ribose)polymerase-1 is an important target enzyme in drug design; inhibitors have a wide variety of therapeutic… 
2009
2009
Review
2005
Review
2005
The poly(ADP-ribose)polymerases (PARPs) catalyse the transfer of ADP-ribose units from the substrate NAD(+) to acceptor proteins… 
Highly Cited
2004
Highly Cited
2004
BACKGROUND Poly (ADP-ribose) polymerase (PARP), a nuclear enzyme activated by strand breaks in DNA, plays an important role in… 
2002
2002
BACKGROUND This study was designed to investigate the effects of 5-aminoisoquinolinone (5-AIQ), a water-soluble potent inhibitor… 
2001
2001
Poly (ADP-ribose) polymerase (PARP), a nuclear enzyme activated by strand breaks in DNA, plays an important role in the tissue… 
Highly Cited
2000
Highly Cited
2000
Poly (ADP‐ribose) synthetase (PARP) is a nuclear enzyme activated by strand breaks in DNA, which are caused inter alia by…