5-Methylcytosine

Known as: 5 methylcytosine, 5-Methylcytosine [Chemical/Ingredient] 
A methylated form of the nucleobase cytosine occurring predominantly in cytosine-phosphate-guanine (CpG) islands that are produced by DNA… (More)

Topic mentions per year

Topic mentions per year

1966-2017
020406019662017

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
The TET (ten–eleven translocation) family of α-ketoglutarate (α-KG)-dependent dioxygenases catalyzes the sequential oxidation of… (More)
  • figure 1
  • figure 2
  • figure 4
Is this relevant?
Highly Cited
2013
Highly Cited
2013
Dynamic changes in 5-methylcytosine (5mC) have been implicated in the regulation of gene expression critical for consolidation of… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2013
Highly Cited
2013
DNA methylation in mammals is highly dynamic during germ cell and preimplantation development but is relatively static during the… (More)
  • figure 1
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2013
Highly Cited
2013
TET dioxygenases successively oxidize 5-methylcytosine (5mC) in mammalian genomes to 5-hydroxymethylcytosine (5hmC), 5… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2013
2013
To uncover the function of and interplay between the mammalian cytosine modifications 5-methylcytosine (5mC) and 5… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2012
Highly Cited
2012
5-Methylcytosine can be converted to 5-hydroxymethylcytosine (5hmC) in mammalian DNA by the ten-eleven translocation (TET… (More)
Is this relevant?
Highly Cited
2011
Highly Cited
2011
Cytosine methylation is the major covalent modification of mammalian genomic DNA and plays important roles in transcriptional… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2009
Highly Cited
2009
DNA cytosine methylation is crucial for retrotransposon silencing and mammalian development. In a computational search for… (More)
  • figure 2
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
1990
Highly Cited
1990
Direct genomic sequencing revealed that cytosine residues known to have undergone a germ-line mutation in the low density… (More)
Is this relevant?
1984
1984
We examined the DNA of Saccharomyces cerevisiae by both HpaII-MspI restriction enzyme digestion and high-performance liquid… (More)
Is this relevant?