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5-Methylcytosine

Known as: 5 methylcytosine, 5-Methylcytosine [Chemical/Ingredient] 
A methylated form of the nucleobase cytosine occurring predominantly in cytosine-phosphate-guanine (CpG) islands that are produced by DNA… Expand
National Institutes of Health

Papers overview

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Review
2017
Review
2017
In mammals, DNA methylation in the form of 5-methylcytosine (5mC) can be actively reversed to unmodified cytosine (C) through TET… Expand
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Highly Cited
2013
Highly Cited
2013
Tet proteins oxidize 5-methylcytosine (mC) to generate 5-hydroxymethyl (hmC), 5-formyl (fC), and 5-carboxylcytosine (caC). The… Expand
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Highly Cited
2012
Highly Cited
2012
5-Methylcytosine can be converted to 5-hydroxymethylcytosine (5hmC) in mammalian DNA by the ten-eleven translocation (TET… Expand
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Highly Cited
2011
Highly Cited
2011
5-methylcytosine (5mC) in DNA plays an important role in gene expression, genomic imprinting, and suppression of transposable… Expand
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Highly Cited
2011
Highly Cited
2011
Cytosine methylation is the major covalent modification of mammalian genomic DNA and plays important roles in transcriptional… Expand
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Highly Cited
2010
Highly Cited
2010
TET2 is a close relative of TET1, an enzyme that converts 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC) in DNA. The… Expand
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Highly Cited
2009
Highly Cited
2009
DNA cytosine methylation is crucial for retrotransposon silencing and mammalian development. In a computational search for… Expand
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Highly Cited
2009
Highly Cited
2009
Despite the importance of epigenetic regulation in neurological disorders, little is known about neuronal chromatin. Cerebellar… Expand
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Highly Cited
1992
Highly Cited
1992
The modulation of DNA-protein interactions by methylation of protein-binding sites in DNA and the occurrence in genomic… Expand
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Highly Cited
1982
Highly Cited
1982
Analysis of the total base composition of DNA from seven different normal human tissues and eight different types of homogeneous… Expand
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