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5,8,11,14-Eicosatetraynoic Acid

Known as: 5,8,11,14 Eicosatetraynoic Acid, 5,8,11,14-Eicosatetraynoic Acid [Chemical/Ingredient], ETYA 
A 20-carbon unsaturated fatty acid containing 4 alkyne bonds. It inhibits the enzymatic conversion of arachidonic acid to prostaglandins E(2) and F… 
National Institutes of Health

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4,7,10,13-eicosatetraynoic acid5,8,11,14-heneicosatetraynoic acidTriarachidonin
In BloodProcess of secretionagonistsanalogs & derivatives

Papers overview

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Highly Cited
1987
Highly Cited
1987
Enhancement by parainfluenza 3 infection of contractile responses to substance P and capsaicin in airway smooth muscle from the guinea pig.
Guinea pigs were inoculated by nasal insufflation with parainfluenza 3 (P-3) or virus growth medium 4 days before performing in… 
1986
1986
Kinins, receptors, antagonists.
Kinins are potent myotropic agents acting on a variety of smooth muscle preparations: isolated arteries, veins, intestines… 
Review
1985
Review
1985
The role of eicosanoids in respiratory mucus hypersecretion.
The role of eicosanoids in the excessive secretion of respiratory mucous glycoproteins (MGP) accompanying immediate… 
Highly Cited
1985
Highly Cited
1985
Suppression of tumor promoter-induced chemiluminescence in mouse epidermal cells by several inhibitors of arachidonic acid metabolism.
The tumor promoter 12-O-tetradecanoylphorbol-13-acetate (TPA) is a stimulator of chemiluminescence (CL) in SENCAR mouse epidermal… 
1984
1984
Beta-endorphin and adrenocorticotropin release from rat adenohypophysis in vitro: evidence for local modulation by arachidonic acid metabolites of the cyclooxygenase and lipoxygenase pathway.
This study was performed to examine an involvement of adenohypophysial arachidonic acid metabolites in the local mechanisms… 
1984
1984
Differential effects of putative lipoxygenase inhibitors on arachidonic acid metabolism in cell-free and intact cell preparations
The effects of nordihydroguairetic acid (NDGA), 3-amino-1-trifluoromethyl-)-phenyl-2-pyrazoline (BW755c), eicostatetraynoic acid… 
Highly Cited
1983
Highly Cited
1983
Spasmogenic properties of platelet-activating factor: evidence for a direct mechanism in the contractile response of pulmonary tissues.
Platelet-activating factor (1-O-alkyl-2-O-acetyl-sn-glycero-3-phosphocholine; PAF) induces a specific, dose-dependent contraction… 
Highly Cited
1983
Highly Cited
1983
The origin of chemiluminescence produced by neutrophils stimulated by opsonized zymosan.
The luminol-dependent chemiluminescence (CL) of neutrophils phagocytosing zymosan is inhibited by superoxide dismutase (SOD… 
1982
1982
Phospholipase A2-induced rat mast cell secretion. Role of arachidonic acid metabolites.
Highly purified porcine phospholipase A2 induced noncytotoxic rat cell degranulation, as indicated by release of histamine… 
1982
1982
Role of lipoxygenase in the O2-dependent activation of soluble guanylate cyclase from rat lung.
Guanylate cyclase activity in rat lung supernatant fractions is stimulated 3-4 fold by aerobic incubation at 30 degrees C for…