5,6,7,8-tetrahydroquinazoline

National Institutes of Health

Papers overview

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2016

2016

Synthesis and biological evaluation of novel 6,7-dihydro-5H-cyclopenta[d]pyrimidine and 5,6,7,8-tetrahydroquinazoline derivatives as sigma-1 (σ1) receptor antagonists for the treatment of pain.

Yu Lan, Yiyan Songyang, Lingli Zhang, Yan Peng, Jinchun Song
Bioorganic & medicinal chemistry letters
2016

The synthesis and biological evaluation of new series of 6,7-dihydro-5H-cyclopenta[d]pyrimidine and 5,6,7,8-tetrahydroquinazoline… (More)

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2015

2015

Discovery of 4,5,6,7-Tetrahydrobenzo[1,2-d]thiazoles as Novel DNA Gyrase Inhibitors Targeting the ATP-Binding Site.

Tihomir Tomašič, Sotirios Katsamakas, +10 authors Danijel Kikelj
Journal of medicinal chemistry
2015

Bacterial DNA gyrase and topoisomerase IV are essential enzymes that control the topological state of DNA during replication and… (More)

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2003

2003

Selective 3-amino-2-pyridinone acetamide thrombin inhibitors incorporating weakly basic partially saturated heterobicyclic P1-arginine mimetics.

Lucija Peterlin-Mašič, Andreja Kranjc, +4 authors Danijel Kikelj
Bioorganic & medicinal chemistry letters
2003

Novel, highly selective and potent thrombin inhibitors were identified as a result of combing the 3-benzylsulfonylamino-2… (More)

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2003

2003

Novel thrombin inhibitors incorporating non-basic partially saturated heterobicyclic P1-arginine mimetics.

Lucija Peterlin-Mašič, Gregor Mlinsek, Tomaz Solmajer, Alenka Trampuš-Bakija, Mojca Stegnar, Danijel Kikelj
Bioorganic & medicinal chemistry letters
2003

The design, synthesis and biological activity of non-covalent thrombin inhibitors incorporating 4,5,6,7-tetrahydroindazole, 2… (More)

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