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5'-nucleotidase activity

Known as: UMPase, 5'-mononucleotidase activity, 5'-AMP nucleotidase 
Catalysis of the reaction: a 5'-ribonucleotide + H2O = a ribonucleoside + phosphate. [EC:3.1.3.5]
National Institutes of Health

Related topics

Related topics

5 relations
5'-NUCLEOTIDASEadenosine monophosphataseuridine monophosphatase

Narrower (2)

snake venom 5'-nucleotidasethimidine monophosphate nucleotidase

Papers overview

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Highly Cited
1994
Highly Cited
1994
Infarct size-limiting effect of ischemic preconditioning is blunted by inhibition of 5'-nucleotidase activity and attenuation of adenosine release.
BACKGROUND We have previously reported that ischemic preconditioning increases 5'-nucleotidase activity and adenosine release… Expand
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Highly Cited
1994
Highly Cited
1994
Alpha 1-adrenoceptor activation mediates the infarct size-limiting effect of ischemic preconditioning through augmentation of 5'-nucleotidase activity.
We have reported that ischemic preconditioning may limit infarct size by increasing 5'-nucleotidase activity. The present study… Expand
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Highly Cited
1993
Highly Cited
1993
Ischemic Preconditioning Increases Adenosine Release and 5′‐Nucleotidase Activity During Myocardial Ischemia and Reperfusion in Dogs Implications for Myocardial Salvage
BackgroundAdenosine has been reported to mediate the necrosis-limiting effects of ischemic preconditioning; however, it is… Expand
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Highly Cited
1986
Highly Cited
1986
The hydrolysis of extracellular adenine nucleotides by cultured endothelial cells from pig aorta. Feed-forward inhibition of adenosine production at the cell surface.
The time course of the extracellular reaction sequence ATP----ADP----AMP----adenosine has been examined during recirculation of… Expand
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Highly Cited
1983
Highly Cited
1983
Reciprocal modulation of growth and differentiated functions of mature rat hepatocytes in primary culture by cell--cell contact and cell membranes.
In primary monolayer cultures of rat mature hepatocytes, many metabolic functions as well as cell growth are regulated by cell… Expand
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Highly Cited
1977
Highly Cited
1977
Surface localization of 5'-nucleotidase on the mouse lymphocyte.
The optimal conditions for the cytochemical localization of 5'-nucleotidase (AMPase) in the mouse lymphocyte have been… Expand
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Highly Cited
1976
Highly Cited
1976
A nonelectrogenic H+ pump in plasma membranes of hog stomach.
Differential and density gradient centrifugation were used to prepare a vesicular membrane fraction from hog gastric mucosa… Expand
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Highly Cited
1975
Highly Cited
1975
Insulin-sensitive phosphodiesterase. Its localization, hormonal stimulation, and oxidative stabilization.
As it was shown previoulsy by others, the membrane-bound phosphodiesterase (cyclic adenosine 3':5'-monophosphate… Expand
Highly Cited
1973
Highly Cited
1973
Properties of a 5'-nucleotidase purified from mouse liver plasma membranes.
1. Extraction of a mouse liver plasma-membrane fraction with a detergent buffer, N-dodecylsarcosinate-Tris buffer (sarcosyl-Tris… Expand
Highly Cited
1966
Highly Cited
1966
Studies on plasma membranes. 3. Mg2+-ATPase,(Na+-K+-Mg2+)-ATPase and 5'-nucleotidase activity of plasma membranes isolated from rat liver.
1. 1. Plasma membranes have been isolated from rat liver and the ATPase (EC 3.6.1.4), (Na+-K+)-ATPase and 5′-nucleotidase (EC 3… Expand
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