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5'-methylthioadenosine phosphorylase activity

Known as: S-methyl-5-thioadenosine:phosphate S-methyl-5-thio-alpha-D-ribosyl-transferase activity, MTA phosphorylase activity, methylthioadenosine nucleoside phosphorylase activity 
Catalysis of the reaction: 5'-methylthioadenosine + phosphate = adenine + 5-methylthio-D-ribose 1-phosphate. [EC:2.4.2.28]
National Institutes of Health

Papers overview

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2001
2001
A 32P-labeled ATP analog, 3’-0-(4-benzoyl)benzoyl ATP (BzATP) previously shown to be an agonist at P,,-purinergic receptors… Expand
  • figure 1
  • figure 3
  • figure 2
  • table I
  • figure 4
1993
1993
Methylthioadenosine phosphorylase (MTAP) is an enzyme that functions in a salvage pathway for adenine synthesis. The locus that… Expand
1992
1992
The absence of 5'-deoxy-5'-methylthioadenosine phosphorylase (MTAase) activity in malignant cells, and the putative localization… Expand
1990
1990
Various adenosine acyclonucleoside derivatives were tested as inhibitors of 5'-deoxy-5'-methylthioadenosine (MeSAdo… Expand
1987
1987
Two human lymphoblastic cell lines, deficient in methylthioadenosine phosphorylase (MTAP) activity, were found to have increased… Expand
1986
1986
5'-Deoxy-5'-methylthioadenosine phosphorylase catalyzes the phosphorolytic cleavage of 5'-deoxy-5'-methylthioadenosine to form 5… Expand
  • table II
  • table 11.2
1984
1984
5'-Deoxy-5'-methylthioadenosine, a naturally occurring co-product of polyamine biosynthesis, has been shown to inhibit a variety… Expand
1983
1983
The enzyme methylthioadenosine phosphorylase functions in both purine and polyamine metabolism is dividing mammalian cells. To… Expand
  • table 11
  • figure 1
  • figure 2
  • table V
  • figure 4
1980
1980
Summary Application of a novel method for microestimation of 5′-deoxy-5′-methylthioadenosine disclosed that several rat tissues… Expand
1980
1980
The effect of castration and subsequent administration of 17 beta-estradiol and testosterone propionate on 5'-methylthioadenosine… Expand