5'-methylthioadenosine phosphorylase activity

Known as: S-methyl-5-thioadenosine:phosphate S-methyl-5-thio-alpha-D-ribosyl-transferase activity, MTA phosphorylase activity, methylthioadenosine nucleoside phosphorylase activity 
Catalysis of the reaction: 5'-methylthioadenosine + phosphate = adenine + 5-methylthio-D-ribose 1-phosphate. [EC:2.4.2.28]
National Institutes of Health

Topic mentions per year

Topic mentions per year

1978-2006
012319782006

Papers overview

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1995
1995
5'-Deoxy-5'-(methylthio)adenosine (MTA) is an S-adenosylmethionine metabolite that is generated as a by-product of polyamine… (More)
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1992
1992
The absence of 5'-deoxy-5'-methylthioadenosine phosphorylase (MTAase) activity in malignant cells, and the putative localization… (More)
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1991
1991
All normal mammalian tissues contain methylthioadenosine phosphorylase, which plays a role in the recycling of purines and… (More)
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1984
1984
5'-Deoxy-5'-methylthioadenosine, a naturally occurring co-product of polyamine biosynthesis, has been shown to inhibit a variety… (More)
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1982
1982
Cells from 20 patients with leukemia and 9 with solid tumors were assayed for the enzyme methylthioadenosine phosphorylase, which… (More)
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1981
1981
Seven out of 31 (23%) human malignant tumor cell lines had no detectable methylthioadenosine phosphorylase activity (less than 0… (More)
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1980
1980
The effect of castration and subsequent administration of 17 beta-estradiol and testosterone propionate on 5'-methylthioadenosine… (More)
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1979
1979
5'-Methylthioadenosine phosphorylase from rat liver has been purified 112-fold. A molecular weight of 90 000 for the enzyme was… (More)
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1979
1979
To determine if increased 5'-methylthioadenosine phosphorylase activity in activated lymphocytes may be responsible for the… (More)
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1978
1978
An enzyme (5'-methylthioadenosine phosphorylase) that catalyzes the phosphorolytic cleavage of 5'-methylthioadenosine to 5… (More)
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