5'-fluoro-5'-deoxyadenosine

Streptomyces cattleya DSM 46488 is unusual in its ability to biosynthesise fluorine containing natural products, where it can… (More)

(3R,4S)-5-Fluoro-5-deoxy-D-ribulose-1-phosphate (5-FDRulP) has been identified as the third fluorinated intermediate on the… (More)

A genomic library of Streptomyces cattleya was screened to isolate a gene cluster encoding enzymes responsible for the production… (More)

Synthesis of 5'-fluoro-5'-deoxyadenosine (5'-FDA) and structurally similar compounds is generally a poor yielding process. This… (More)

The C-F bond-forming step in the fluorinase, the only native fluorination enzyme characterized to date, has been studied. The… (More)

5'-Fluoro-5'-deoxyinosine (5'-FDI) is identified as an adventitious side product that accumulates in cell free incubations of SAM… (More)

Fluorine is the thirteenth most abundant element in the earth's crust, but fluoride concentrations in surface water are low and… (More)

The stereochemical course of the recently isolated fluorination enzyme from Streptomyces cattleya has been evaluated. The enzyme… (More)

Organofluorine compounds are widely prepared throughout the chemicals industry, but their prepararion generally requires harsh… (More)

5'-fluorodeoxyadenosine synthase, a C-F bond-forming enzyme, has been purified from Streptomyces cattleya. The enzyme mediates a… (More)