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5'-3'-Exonucleases

Known as: 5' 3' Exonuclease, 5'-3' Exonuclease, 5'-3'-Exonuclease 
Five Prime-Three Prime Exonucleases specifically catalyze the hydrolysis of terminal phosphodiester bonds of nucleic acids. Human XRN1 and XRN2 are… 
National Institutes of Health

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3'-5'-ExonucleasesAPEX1 protein, humanCell NucleusDCLRE1B protein, human

Broader (1)

Exonuclease

Papers overview

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2006
2006
Mechanism of adenomatous polyposis coli (APC)-mediated blockage of long-patch base excision repair.
Recently, we found an interaction between adenomatous polyposis coli (APC) and DNA polymerase beta (pol-beta) and showed that APC… 
2004
2004
DmGEN, a novel RAD2 family endo-exonuclease from Drosophila melanogaster.
A novel endo-exonuclease, DmGEN (Drosophila Melanogaster XPG-like endonuclease), was identified in D.melanogaster. DmGEN is… 
2001
2001
Biochemical Analysis of Point Mutations in the 5′-3′ Exonuclease of DNA Polymerase I of Streptococcus pneumoniae
To define the active site of the 5′-3′ exonucleolytic domain of the Streptococcus pneumoniae DNA polymerase I (Spn pol I), we… 
1998
1998
A 5'-3' exonuclease activity involved in forming the 3' products of histone pre-mRNA processing in vitro.
Histone RNA 3' processing in vitro produces one or more 5' cleavage products corresponding to the mature histone mRNA 3' end, and… 
Highly Cited
1998
Highly Cited
1998
Homologous recombination is required for the viability of rad27 mutants.
The RAD27/RTH1 gene of Saccharomyces cerevisiae encodes a structural and functional homolog of the 5'-3' exonuclease function of… 
Highly Cited
1997
Highly Cited
1997
Characterization of a DNA polymerase from the uncultivated psychrophilic archaeon Cenarchaeum symbiosum
Cenarchaeum symbiosum, an archaeon which lives in specific association with a marine sponge, belongs to a recently recognized… 
1995
1995
Cloning and sequence analysis of the gene encoding the DNA polymerase I from Mycobacterium tuberculosis.
1991
1991
Overexpression, purification, and characterization of Escherichia coli bacteriophage PRD1 DNA polymerase. In vitro synthesis of full-length PRD1 DNA with purified proteins.
1989
1989
Conditional lethality of the recA441 and recA730 mutants of Escherichia coli deficient in DNA polymerase I.
1986
1986
Host and phage-coded functions required for coliphage N4 DNA replication.
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