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4a-hydroxytetrahydrobiopterin dehydratase

Known as: pterin-4a-carbinolamine dehydratase, pterin-4alpha-carbinolamine dehydratase, dimerization cofactor of HNF-1alpha 
 
National Institutes of Health

Papers overview

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2014
2014
Ribulose-1,5-bisphosphate carboxylase/oxygenase (Rubisco) plays a critical role in sustaining life by catalysis of carbon… Expand
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Review
2011
Review
2011
BH4 (6R-L-erythro-5,6,7,8-tetrahydrobiopterin) is an essential cofactor of a set of enzymes that are of central metabolic… Expand
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Highly Cited
2009
Highly Cited
2009
Dopa-responsive dystonia is a childhood-onset dystonic disorder, characterized by a dramatic response to low dose of L-Dopa. Dopa… Expand
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2005
2005
SummaryApproximately 2% of newborns with hyperphenylalaninaemia are deficient in tetrahydrobiopterin. Selective screening must be… Expand
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Highly Cited
2004
Highly Cited
2004
Previously it has been demonstrated that the human epidermis synthesises and degrades acetylcholine and expresses both muscarinic… Expand
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Highly Cited
2002
Highly Cited
2002
The prevalence of type 2 diabetes mellitus in the Oji-Cree of northwestern Ontario is the third highest in the world. A private… Expand
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Review
2002
Review
2002
Tetrahydrobiopterin (BH4) deficiencies are disorders affecting phenylalanine metabolism in liver and neurotransmitters… Expand
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Review
2000
Review
2000
Tetrahydrobiopterin (BH(4)) cofactor is essential for various processes, and is present in probably every cell or tissue of… Expand
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Highly Cited
1999
Highly Cited
1999
Dacarbazine (DTIC), a widely used anticancer agent, is inactive until metabolized in the liver by cytochromes P450 to form the… Expand
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Review
1996
Review
1996
Tetrahydrobiopterin deficiency, a variant of hyperphenylalaninemia, may be caused by deficiency of one of the following enzymes… Expand
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