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4a-hydroxytetrahydrobiopterin dehydratase

Known as: pterin-4a-carbinolamine dehydratase, pterin-4alpha-carbinolamine dehydratase, dimerization cofactor of HNF-1alpha 
 
National Institutes of Health

Papers overview

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Review
2011
Review
2011
BH4 (6R-L-erythro-5,6,7,8-tetrahydrobiopterin) is an essential cofactor of a set of enzymes that are of central metabolic… Expand
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Highly Cited
2009
Highly Cited
2009
Dopa-responsive dystonia is a childhood-onset dystonic disorder, characterized by a dramatic response to low dose of L-Dopa. Dopa… Expand
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Highly Cited
2005
Highly Cited
2005
SummaryApproximately 2% of newborns with hyperphenylalaninaemia are deficient in tetrahydrobiopterin. Selective screening must be… Expand
Highly Cited
2004
Highly Cited
2004
Previously it has been demonstrated that the human epidermis synthesises and degrades acetylcholine and expresses both muscarinic… Expand
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Highly Cited
2002
Highly Cited
2002
The prevalence of type 2 diabetes mellitus in the Oji-Cree of northwestern Ontario is the third highest in the world. A private… Expand
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Review
2002
Review
2002
  • H. Shintaku
  • Current drug metabolism
  • 2002
  • Corpus ID: 11743250
Tetrahydrobiopterin (BH4) deficiencies are disorders affecting phenylalanine metabolism in liver and neurotransmitters… Expand
Review
2000
Review
2000
Tetrahydrobiopterin (BH(4)) cofactor is essential for various processes, and is present in probably every cell or tissue of… Expand
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Highly Cited
1999
Highly Cited
1999
Dacarbazine (DTIC), a widely used anticancer agent, is inactive until metabolized in the liver by cytochromes P450 to form the… Expand
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1990
1990
A series of 4- and 5-[2,3-dihydro-6,7-bis[[(N-alkylcarbamoyl)oxy]methyl]-1H-pyrrol izin-5- yl]-2-halopyridinium iodides were… Expand
1989
1989
In the presence of phenylalanine and molecular oxygen, activated phenylalanine hydroxylase catalyzes the oxidation of… Expand
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