4a-hydroxytetrahydrobiopterin dehydratase activity

Known as: 4-alpha-hydroxy-tetrahydropterin dehydratase activity, pterin-4-alpha-carbinolamine dehydratase activity, 4alpha-hydroxy-tetrahydropterin dehydratase activity 
Catalysis of the reaction: (6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin = (6R)-6-(L-erythro-1,2-dihydroxypropyl)-7,8… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1982-2016
02419822016

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2014
2014
Ribulose-1,5-bisphosphate carboxylase/oxygenase (Rubisco) plays a critical role in sustaining life by catalysis of carbon… (More)
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2010
2010
Tetrahydromonapterin is a major pterin in Escherichia coli and is hypothesized to be the cofactor for phenylalanine hydroxylase… (More)
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2009
2009
Dopa-responsive dystonia is a childhood-onset dystonic disorder, characterized by a dramatic response to low dose of L-Dopa. Dopa… (More)
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2008
2008
Pterin-4a-carbinolamine dehydratases (PCDs) recycle oxidized pterin cofactors generated by aromatic amino acid hydroxylases (AAHs… (More)
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2005
2005
The interstrand N2,N2-dG DNA cross-linking chemistry of the acrolein-derived gamma-OH-1,N2-propanodeoxyguanosine (gamma-OH-PdG… (More)
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2004
2004
Previously it has been demonstrated that the human epidermis synthesises and degrades acetylcholine and expresses both muscarinic… (More)
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2003
2003
Human epidermal melanocytes hold the full capacity for autocrine de novo synthesis/regulation/recycling of the essential cofactor… (More)
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2001
2001
Drosophila enhancer of rudimentary [e(r)] interacts genetically with the rudimentary gene, which encodes a protein possessing the… (More)
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1999
1999
Pterin 4a-carbinolamine dehydratase is bifunctional in mammals. In addition to playing a catalytic role in pterin recycling in… (More)
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1983
1983
Hexamethylmelamine (HMM) is metabolized by rat hepatic microsomal preparations to reactive species which covalently bind to… (More)
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