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4-vinyl-1-cyclohexene dioxide

Known as: 3-Oxiranyl-7-oxabicyclo[4.1.0]heptane, 1-Epoxyethyl-3,4-epoxycyclohexane, 3-oxiranyl- 7-oxabicyclo(4.1.0)heptane 
A synthetic, colorless liquid that is soluble in water. It is used as a reactive diluent for other epoxides and as a monomer in the production of… Expand
National Institutes of Health

Related topics

Related topics

3 relations

Broader (3)

CarcinogensCyclohexenesVinyl Compounds

Papers overview

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Review
2012
Review
2012
An update on primary ovarian insufficiency
Primary ovarian insufficiency (POI) occurs in about 1% of female population under the age of 40, leading to reproductive problems… Expand
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2010
2010
Degradation of volatile organic compounds in a non-thermal plasma air purifier.
The degradation of volatile organic compounds in a commercially available non-thermal plasma based air purifying system was… Expand
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2009
2009
Loss of ovarian function in the VCD mouse-model of menopause leads to insulin resistance and a rapid progression into the metabolic syndrome.
Factors comprising the metabolic syndrome occur with increased incidence in postmenopausal women. To investigate the effects of… Expand
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2009
2009
Effect of phosphatidylinositol-3 kinase inhibition on ovotoxicity caused by 4-vinylcyclohexene diepoxide and 7, 12-dimethylbenz[a]anthracene in neonatal rat ovaries.
4-vinylcyclohexene diepoxide (VCD) is an ovotoxicant that specifically destroys primordial and small primary follicles in the… Expand
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Highly Cited
2006
Highly Cited
2006
Accelerated ovarian failure induced by 4-vinyl cyclohexene diepoxide in Nrf2 null mice.
Genetic and biochemical analyses have uncovered an essential role for nuclear factor erythroid 2-related factor 2 (Nrf2) in… Expand
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2005
2005
Atherosclerotic lesion development in a novel ovary-intact mouse model of perimenopause.
OBJECTIVE Since the unexpected results from the Women's Health Initiative, the possible protective role of estrogen in preventing… Expand
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Highly Cited
2004
Highly Cited
2004
Particle phase acidity and oligomer formation in secondary organic aerosol.
A series of controlled laboratory experiments are carried out in dual Teflon chambers to examine the presence of oligomers in… Expand
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Highly Cited
2002
Highly Cited
2002
Long-term effects of ovarian follicular depletion in rats by 4-vinylcyclohexene diepoxide.
4-Vinylcyclohexene diepoxide (VCD) destroys preantral ovarian follicles in rats. Female 28-day Fisher 344 (F344) rats were dosed… Expand
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1996
1996
Enhanced expression of bax in small preantral follicles during 4-vinylcyclohexene diepoxide-induced ovotoxicity in the rat.
4-Vinylcyclohexene diepoxide (VCD) destroys small preantral (25-100 microns) ovarian follicles after repeated dosing in mice and… Expand
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Highly Cited
1994
Highly Cited
1994
Destruction of preantral follicles in adult rats by 4-vinyl-1-cyclohexene diepoxide.
4-vinyl-1-cyclohexene diepoxide (VCD) is known to destroy oocytes in ovaries of immature rats. Since ovaries functionally differ… Expand
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