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4-vinyl-1-cyclohexene dioxide

Known as: 3-Oxiranyl-7-oxabicyclo[4.1.0]heptane, 1-epoxyethyl-3,4-epoxycyclohexane, 3-oxiranyl- 7-oxabicyclo(4.1.0)heptane 
A synthetic, colorless liquid that is soluble in water. It is used as a reactive diluent for other epoxides and as a monomer in the production of… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1976-2017
0519762017

Related topics

Related topics

3 relations

Broader (3)

CarcinogensCyclohexenesVinyl Compounds

Related mentions per year

Related mentions per year

1939-2018
19401960198020002020
4-vinyl-1-cyclohexene dioxide
Carcinogens
Cyclohexenes
Vinyl Compounds

Papers overview

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2010
2010
The cognitive effects of conjugated equine estrogens depend on whether menopause etiology is transitional or surgical.
The question of whether to take hormone therapy (HT) will impact every woman as she enters reproductive senescence. In women… (More)
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2008
2008
Comparison of Skeletal Effects of Ovariectomy Versus Chemically Induced Ovarian Failure in Mice
Bone loss associated with menopause leads to an increase in skeletal fragility and fracture risk. Relevant animal models can be… (More)
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2007
2007
Hormonal status affects the progression of STZ-induced diabetes and diabetic renal damage in the VCD mouse model of menopause.
Changes in the estrogen/testosterone balance at menopause may negatively influence the development of diabetic kidney disease… (More)
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2006
2006
Accelerated ovarian failure induced by 4-vinyl cyclohexene diepoxide in Nrf2 null mice.
Genetic and biochemical analyses have uncovered an essential role for nuclear factor erythroid 2-related factor 2 (Nrf2) in… (More)
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2004
2004
The follicle-deplete mouse ovary produces androgen.
The follicle-depleted postmenopausal ovary is enriched in interstitial cells that produce androgens. This study was designed to… (More)
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2002
2002
Long-term effects of ovarian follicular depletion in rats by 4-vinylcyclohexene diepoxide.
4-Vinylcyclohexene diepoxide (VCD) destroys preantral ovarian follicles in rats. Female 28-day Fisher 344 (F344) rats were dosed… (More)
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2001
2001
Apoptosis induced in rats by 4-vinylcyclohexene diepoxide is associated with activation of the caspase cascades.
Previous studies have shown that ovotoxicity induced in rats by dosing with 4-vinylcyclohexene diepoxide (VCD) is likely via… (More)
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1999
1999
Early effects of ovotoxicity induced by 4-vinylcyclohexene diepoxide in rats and mice.
The industrial chemical 4-vinylcyclohexene diepoxide (VCD) causes specific destruction of oocyte-containing small preantral… (More)
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1996
1996
Involvement of apoptosis in 4-vinylcyclohexene diepoxide-induced ovotoxicity in rats.
Previous studies have determined that 4-vinylcyclohexene diepoxide (VCD) causes specific destruction of oocytes contained in… (More)
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1989
1989
Testing for increased carcinogenicity using a survival-adjusted quantal response test.
The linear trend test in proportions is frequently used to analyze the results of animal carcinogenicity experiments. This test… (More)
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