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4-phenyl-4-piperidinocyclohexanol

Known as: 1-(1-phenyl-4-hydroxycyclohexyl)piperidine, 4-phenyl-4-(1-piperidinyl)cyclohexanol 
 
National Institutes of Health

Papers overview

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1996
1996
We developed an analytical method for the simultaneous detection of phencyclidine (PCP) and its metabolites, 4-phenyl-4… Expand
1994
1994
The major metabolite of phencyclidine (PCP), the trans isomer of 4-phenyl-4-(1-piperidinyl)cyclohexanol [(trans)-4-PPC… Expand
1994
1994
To elucidate the biological activity of natural metabolites of phencyclidine (PCP), we examined the behavioral effects of a major… Expand
1987
1987
In vivo administration of phencyclidine (PCP) has been shown to enhance the accumulation of intravenously administered 3H… Expand
1984
1984
A series of phencyclidine (PCP) related analogs, carbonitrile synthetic precursors and two monohydroxylated metabolites were… Expand
Highly Cited
1982
Highly Cited
1982
[3H]‐Phencyclidine (PCP) hydrochloride was given in intravenous (0.1 or 1 mg) or oral (1 mg) doses to male subjects. After 1 mg… Expand
1982
1982
The following monohydroxy derivatives of 1-(1-phenylcyclohexyl)piperidine (phencyclidine, PCP) were synthesized: o-, m-, and p… Expand
1981
1981
One of the major biotransformation pathways in the metabolism of phencyclidine is hydroxylation at C-4 of the cyclohexane ring to… Expand
1981
1981
A number of microorganisms were screened for their ability to metabolize phencyclidine. Two microorganisms, Beauveria… Expand
1981
1981
The in vitro metabolism of phencyclidine by rabbit liver 9000g supernatant fraction produces primarily three known hydroxylated… Expand