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4-phenyl-4-piperidinocyclohexanol
Known as:
1-(1-phenyl-4-hydroxycyclohexyl)piperidine
, 4-phenyl-4-(1-piperidinyl)cyclohexanol
National Institutes of Health
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2 relations
Broader (1)
Phencyclidine
analogs & derivatives
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
1996
1996
Hair analysis for drugs of abuse XII. Determination of PCP and its major metabolites, PCHP and PPC, in rat hair after administration of PCP.
T. Sakamoto
,
A. Tanaka
,
Y. Nakahara
Journal of analytical toxicology
1996
Corpus ID: 23835685
We developed an analytical method for the simultaneous detection of phencyclidine (PCP) and its metabolites, 4-phenyl-4…
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1994
1994
Effects of the major metabolite of phencyclidine, the trans isomer of 4-phenyl-4-(1-piperidinyl)cyclohexanol, on [3H]N-(1-[2-thienyl]cyclohexyl)-3,4-piperidine ([3H]TCP) binding and [3H]dopamine…
A. Baba
,
Toshifumi Yamamoto
,
Hideko Yamamoto
,
Toshihito Suzuki
,
T. Moroji
Neuroscience Letters
1994
Corpus ID: 13495441
1994
1994
Behavioral effects of phencyclidine and its major metabolite, (trans)4-phenyl-4-(1-piperidinyl)cyclohexanol, in mice
A. Baba
,
Toshifumi Yamamoto
,
N. Kawai
,
Hideko Yamamoto
,
Toshihito Suzuki
,
T. Moroji
Behavioural Brain Research
1994
Corpus ID: 39658282
1987
1987
Doubtful role for phenycyclidine metabolites in PCP enhancement of QNB binding
W. Boggan
,
L. Middaugh
Pharmacology Biochemistry and Behavior
1987
Corpus ID: 32676692
1984
1984
Phencyclidine analogs and precursors: rotarod and lethal dose studies in the mouse.
D. B. Vaupel
,
D. McCoun
,
E. Cone
The Journal of pharmacology and experimental…
1984
Corpus ID: 25365820
A series of phencyclidine (PCP) related analogs, carbonitrile synthetic precursors and two monohydroxylated metabolites were…
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Highly Cited
1982
Highly Cited
1982
Phencyclidine disposition after intravenous and oral doses
C. Edgar Cook
,
D. Brine
,
+4 authors
S. Di Guiseppi
Clinical pharmacology and therapeutics
1982
Corpus ID: 12787107
[3H]‐Phencyclidine (PCP) hydrochloride was given in intravenous (0.1 or 1 mg) or oral (1 mg) doses to male subjects. After 1 mg…
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1982
1982
Chemical synthesis and molecular pharmacology of hydroxylated 1-(1-phenylcyclohexyl-piperidine derivatives.
J. Kamenka
,
B. Chiche
,
+4 authors
M. Lazdunski
Journal of medicinal chemistry
1982
Corpus ID: 8782412
The following monohydroxy derivatives of 1-(1-phenylcyclohexyl)piperidine (phencyclidine, PCP) were synthesized: o-, m-, and p…
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1981
1981
Phencyclidine metabolism: resolution, structure, and biological activity of the isomers of the hydroxy metabolite, 4-phenyl-4-(1-piperidinyl)cyclohexanol.
F. Carroll
,
G. Brine
,
+4 authors
W. Buchwald
Journal of medicinal chemistry
1981
Corpus ID: 45008114
One of the major biotransformation pathways in the metabolism of phencyclidine is hydroxylation at C-4 of the cyclohexane ring to…
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1981
1981
The metabolism of phencyclidine by rabbit liver preparations.
R. Kammerer
,
D. Schmitz
,
E. Distefano
,
A. Cho
Drug metabolism and disposition: the biological…
1981
Corpus ID: 29199321
The in vitro metabolism of phencyclidine by rabbit liver 9000g supernatant fraction produces primarily three known hydroxylated…
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1981
1981
Metabolism of phencyclidine by microorganisms.
C. D. Hufford
,
J. K. Baker
,
A. Clark
Journal of pharmaceutical sciences
1981
Corpus ID: 8958439
A number of microorganisms were screened for their ability to metabolize phencyclidine. Two microorganisms, Beauveria…
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