4-hydroxyperoxycyclophosphamide

Metastasis to the bone is seen in 56% of patients with neuroblastoma and contributes to morbidity and mortality. Using a murine… Expand

Cholangiocarcinoma is markedly resistant to chemotherapy and has a dismal prognosis, but its mechanism of drug resistance is… Expand

Red grape seed extract containing proanthocyanidins and other antioxidants are being used as nutritional supplements by many… Expand

In an attempt to ameliorate the chemotherapy associated normal cell toxicity, in this study a known antioxidant, grape seed… Expand

High-dose chemotherapy with autologous stem cell transplantation is an increasingly used procedure in oncohematologic diseases… Expand

Human chronic myelogenous leukemia (CML) is a unique malignancy in its cellular and molecular phenotypes. High dose therapy… Expand

Objective To determine whether chemotherapy drugs elicit programmed cell death (apoptosis) in ovarian cancer cells. Methods… Expand

Treatment of T cells in vitro with low concentrations of 4-hydroperoxycyclophosphamide (4-HC) is known to result in… Expand

The alkylating agents represent one of the most important classes of antitumor agents and play a major role in combination with… Expand

The human tumor colony-forming assay was used to compare primary tumors with their metastases. Cell suspensions were prepared… Expand