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Metastasis to the bone is seen in 56% of patients with neuroblastoma and contributes to morbidity and mortality. Using a murine… (More)
L-buthionine sulfoximine (BSO) inhibits glutathione synthesis and may modulate tumor resistance to some alkylating… (More)
In an attempt to ameliorate the chemotherapy associated normal cell toxicity, in this study a known antioxidant, grape seed… (More)
- Journal of Neuro-Oncology
To individually tailor chemotherapy for patients with malignant gliomas according to tumor chemosensitivity, a rapid assay system… (More)
- International journal of oncology
Human chronic myelogenous leukemia (CML) is a unique malignancy in its cellular and molecular phenotypes. High dose therapy… (More)
- Obstetrics and gynecology
To determine whether chemotherapy drugs elicit programmed cell death (apoptosis) in ovarian cancer cells.
Treatment of T cells in vitro with low concentrations of 4-hydroperoxycyclophosphamide (4-HC) is known to result in… (More)
The alkylating agents represent one of the most important classes of antitumor agents and play a major role in combination with… (More)
The human tumor colony-forming assay was used to compare primary tumors with their metastases. Cell suspensions were prepared… (More)
- The Journal of experimental medicine
As measured by [(3)H]thymidine uptake, spleen cells of mice injected 7 d previously with a single dose of cyclophosphamide (Cy… (More)