FAQ

4-hydroxyperoxycyclophosphamide

Known as: 4-HOO-CP, 4-hydroxyperoxy-cyclophosphamide 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1979-2016
01219792016

Related topics

Related topics

1 relation

Broader (1)

Cyclophosphamide

Related mentions per year

Related mentions per year

1945-2018
19401960198020002020
4-hydroxyperoxycyclophosphamide
Cyclophosphamide

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2007
2007
The activity of zoledronic Acid on neuroblastoma bone metastasis involves inhibition of osteoclasts and tumor cell survival and proliferation.
Metastasis to the bone is seen in 56% of patients with neuroblastoma and contributes to morbidity and mortality. Using a murine… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2001
2001
L-buthionine sulfoximine potentiates the antitumor effect of 4-hydroperoxycyclophosphamide when administered locally in a rat glioma model.
OBJECTIVE L-buthionine sulfoximine (BSO) inhibits glutathione synthesis and may modulate tumor resistance to some alkylating… (More)
Is this relevant?
2000
2000
Chemopreventive effects of grape seed proanthocyanidin extract on Chang liver cells.
In an attempt to ameliorate the chemotherapy associated normal cell toxicity, in this study a known antioxidant, grape seed… (More)
Is this relevant?
1998
1998
Unexpected in vitro chemosensitivity of malignant gliomas to 4-hydroxyperoxycyclophosphamide (4-HC)
To individually tailor chemotherapy for patients with malignant gliomas according to tumor chemosensitivity, a rapid assay system… (More)
  • figure 1
  • figure 2
  • table 1
  • table 2
  • table 3
Is this relevant?
1997
1997
Increased growth inhibition of human chronic myelogenous leukemic cells by a combination of c-myb antisense oligonucleotide and 4-hydroxyperoxycyclophosphamide in vitro.
Human chronic myelogenous leukemia (CML) is a unique malignancy in its cellular and molecular phenotypes. High dose therapy… (More)
Is this relevant?
1995
1995
Chemotherapy-induced apoptosis in epithelial ovarian cancers.
OBJECTIVE To determine whether chemotherapy drugs elicit programmed cell death (apoptosis) in ovarian cancer cells. METHODS… (More)
Is this relevant?
1987
1987
In vitro effects of 4-hydroxyperoxycyclophosphamide on human immunoregulatory T subset function.
Treatment of T cells in vitro with low concentrations of 4-hydroperoxycyclophosphamide (4-HC) is known to result in… (More)
Is this relevant?
Highly Cited
1986
Highly Cited
1986
Alkylating agents: in vitro studies of cross-resistance patterns in human cell lines.
The alkylating agents represent one of the most important classes of antitumor agents and play a major role in combination with… (More)
  • table 1
  • figure 2
  • figure 1
  • table 2
  • figure 3
Is this relevant?
1982
1982
Heterogeneity in growth pattern and drug sensitivity of primary tumor and metastases in the human tumor colony-forming assay.
The human tumor colony-forming assay was used to compare primary tumors with their metastases. Cell suspensions were prepared… (More)
Is this relevant?
1979
1979
T-suppressor cells sensitive to cyclophosphamide and to its in vitro active derivative 4-hydroperoxycyclophosphamide control the mitogenic response of murine splenic B cells to dextran sulfate. A…
As measured by [(3)H]thymidine uptake, spleen cells of mice injected 7 d previously with a single dose of cyclophosphamide (Cy… (More)
  • table I
Is this relevant?