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4-hydroxyperoxycyclophosphamide

Known as: 4-HOO-CP, 4-hydroxyperoxy-cyclophosphamide 
National Institutes of Health

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2 relations

Broader (1)

Cyclophosphamide
analogs & derivatives

Papers overview

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2016
2016
Aldehyde dehydrogenase 3A1 promotes multi-modality resistance and alters gene expression profile in human breast adenocarcinoma MCF-7 cells.
Highly Cited
2007
Highly Cited
2007
The activity of zoledronic Acid on neuroblastoma bone metastasis involves inhibition of osteoclasts and tumor cell survival and proliferation.
Metastasis to the bone is seen in 56% of patients with neuroblastoma and contributes to morbidity and mortality. Using a murine… 
Highly Cited
2003
Highly Cited
2003
Reversal of Multiple Drug Resistance in Cholangiocarcinoma by the Glutathione S-Transferase-π-Specific Inhibitor O1-Hexadecyl-γ-glutamyl-S-benzylcysteinyl-D-phenylglycine Ethylester
Cholangiocarcinoma is markedly resistant to chemotherapy and has a dismal prognosis, but its mechanism of drug resistance is… 
Highly Cited
2000
Highly Cited
2000
Chemopreventive effects of grape seed proanthocyanidin extract on Chang liver cells.
Review
1999
Review
1999
Ex vivo manipulation of hematopoietic stem cells for transplantation: the potential role of amifostine.
High-dose chemotherapy with autologous stem cell transplantation is an increasingly used procedure in oncohematologic diseases… 
Highly Cited
1995
Highly Cited
1995
Chemotherapy‐Induced Apoptosis in Epithelial Ovarian Cancers
Review
1990
Review
1990
Etoposide. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in combination chemotherapy of cancer.
1987
1987
In vitro effects of 4-hydroxyperoxycyclophosphamide on human immunoregulatory T subset function.
Treatment of T cells in vitro with low concentrations of 4-hydroperoxycyclophosphamide (4-HC) is known to result in… 
Highly Cited
1986
Highly Cited
1986
Alkylating agents: in vitro studies of cross-resistance patterns in human cell lines.
The alkylating agents represent one of the most important classes of antitumor agents and play a major role in combination with… 
Highly Cited
1982
Highly Cited
1982
Heterogeneity in growth pattern and drug sensitivity of primary tumor and metastases in the human tumor colony-forming assay.
The human tumor colony-forming assay was used to compare primary tumors with their metastases. Cell suspensions were prepared… 
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