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4-hydroxyatomoxetine

 
National Institutes of Health

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2 relations

Broader (2)

PhenolsPropylamines

Papers overview

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2016
2016
The Effect of Myricetin on Pharmacokinetics of Atomoxetine and its Metabolite 4-Hydroxyatomoxetine In Vivo and In Vitro
Background and ObjectivesAtomoxetine is the first non-stimulant drug to be approved for the treatment of ADHD, while the effect… Expand
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2012
2012
Determination of atomoxetine and its metabolites in conventional and non-conventional biological matrices by liquid chromatography-tandem mass spectrometry.
A procedure based on liquid chromatography-tandem mass spectrometry (LC-MS/MS) is described for determination of atomoxetine (ATX… Expand
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Review
2005
Review
2005
Clinical Pharmacokinetics of Atomoxetine
Atomoxetine (Strattera®), a potent and selective inhibitor of the presynaptic norepinephrine transporter, is used clinically for… Expand
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2004
2004
Atomoxetine hydrochloride: clinical drug-drug interaction prediction and outcome.
In the studies reported here, the ability of atomoxetine hydrochloride (Strattera) to inhibit or induce the metabolic… Expand
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Highly Cited
2003
Highly Cited
2003
Disposition and metabolic fate of atomoxetine hydrochloride: the role of CYP2D6 in human disposition and metabolism.
The role of the polymorphic cytochrome p450 2D6 (CYP2D6) in the pharmacokinetics of atomoxetine hydrochloride [(-)-N-methyl-gamma… Expand
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2003
2003
Atomoxetine pharmacokinetics in children and adolescents with attention deficit hyperactivity disorder.
OBJECTIVE Atomoxetine is indicated for the treatment of attention deficit hyperactivity disorder in children, adolescents, and… Expand
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2003
2003
Disposition and metabolic fate of atomoxetine hydrochloride: pharmacokinetics, metabolism, and excretion in the Fischer 344 rat and beagle dog.
These studies were designed to characterize the disposition and metabolism of atomoxetine hydrochloride [(-)-N-methyl-gamma-(2… Expand
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2003
2003
Effect of hepatic impairment on the pharmacokinetics of atomoxetine and its metabolites.
BACKGROUND AND OBJECTIVES Atomoxetine is a treatment for attention-deficit/hyperactivity disorder and is primarily eliminated via… Expand
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2002
2002
Identification of the human cytochromes P450 responsible for atomoxetine metabolism.
Studies were performed to determine the human enzymes responsible for the biotransformation of atomoxetine to its major… Expand
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2002
2002
Effect of potent CYP2D6 inhibition by paroxetine on atomoxetine pharmacokinetics.
The purpose of this study was to characterize the effect of potent CYP2D6 inhibition byparoxetine on atomoxetine disposition in… Expand
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