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4-chloro-3-hydroxyanthranilic acid

Known as: 4-Cl-3-hana, 4-chloro-3-hydroxyanthranilate, Benzoic acid, 2-amino-4-chloro-3-hydroxy- 
 
National Institutes of Health

Papers overview

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2006
2006
Inflammatory processes within the central nervous system (CNS) contribute significantly to the pathogenesis of a broad range of… Expand
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2005
2005
3-Hydroxyanthranilate-3,4-dioxygenase (HAD) is a non-heme Fe(II) dependent enzyme that catalyzes the oxidative ring-opening of 3… Expand
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1995
1995
Quinolinic acid (QUIN) is an excitotoxic tryptophan metabolite that is produced by activated macrophages. Accumulations of QUIN… Expand
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1995
1995
The metabolism of L-tryptophan to the neuroactive kynurenine pathway metabolites, L-kynurenine, kynurenate and quinolinate, and… Expand
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1994
1994
Accumulations of the neurotoxin quinolinic acid (QUIN) occur in the brain and blood following immune activation and are… Expand
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1994
1994
Quinolinic acid (QUIN) is a potential pathogen in a variety of excitotoxic and neuroviral brain diseases. In the present study… Expand
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Highly Cited
1993
Highly Cited
1993
Quinolinic acid (QUIN), kynurenic acid (KYNA) and L-kynurenine (L-KYN) are neuroactive kynurenine pathway metabolites that… Expand
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1990
1990
As assessed by HPLC with electrochemical detection, 3-hydroxyanthranilic acid (3-HANA) was found to be present in the rat brain… Expand
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1988
1988
Quinolinic acid is synthesized from 3-hydroxyanthranilic acid via 3-hydroxyanthranilic acid oxidase. In liver, 4-chloro-3… Expand
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1980
1980
Abstract Rats and guinea pigs dosed with dl -6-chlorotryptophan or d -6-chlorotryptophan excrete significantly greater amounts of… Expand
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