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4-chloro-3-hydroxyanthranilic acid

Known as: 4-Cl-3-hana, 4-chloro-3-hydroxyanthranilate, Benzoic acid, 2-amino-4-chloro-3-hydroxy- 
National Institutes of Health

Papers overview

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2005
2005
3-Hydroxyanthranilate-3,4-dioxygenase (HAD) is a non-heme Fe(II) dependent enzyme that catalyzes the oxidative ring-opening of 3… 
2000
2000
Excitotoxic mechanisms may play a critical role in the pathophysiology of several neurological and psychiatric diseases… 
Highly Cited
1995
Highly Cited
1995
Quinolinic acid (QUIN) is an excitotoxic tryptophan metabolite that is produced by activated macrophages. Accumulations of QUIN… 
1995
1995
Abstract: The metabolism of l‐tryptophan to the neuroactive kynurenine pathway metabolites, l‐kynurenine, kynurenate and… 
Highly Cited
1993
Highly Cited
1993
Quinolinic acid (QUIN), kynurenic acid (KYNA) and L-kynurenine (L-KYN) are neuroactive kynurenine pathway metabolites that… 
Review
1993
Review
1993
Accumulation of quinolinic acid and L-kynurenine occurs in the brain and/or blood following immune activation, and may derive… 
Highly Cited
1990
Highly Cited
1990
Abstract: As assessed by HPLC with electrochemical detection, 3‐hydroxyanthranilic acid (3‐HANA) was found to be present in the…