4-aminoquinoline

 
National Institutes of Health

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Highly Cited
2012
Highly Cited
2012
Chloroquine (CQ) is a 4-aminoquinoline drug used for the treatment of diverse diseases. It inhibits lysosomal acidification and… (More)
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Highly Cited
2009
Highly Cited
2009
Chloroquine (CQ) resistance (CQR) in Plasmodium falciparum originated from at least six foci in South America, Asia, and Oceania… (More)
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2005
2005
This study describes the synthesis of new 4-aminoquinoline derivatives and evaluation of their activity against a chloroquine… (More)
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2004
2004
Due to growing problems with drug resistance, there is an outstanding need for new, cost-effective drugs for the treatment of… (More)
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2003
2003
The spread of chloroquine-resistant Plasmodium falciparum calls for a constant search for new drugs. The in vitro activity of… (More)
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2002
2002
Antiplasmodial activities versus the chloroquine sensitive D10 strain of Plasmodium falciparum of a series of N(1),N(1)-diethyl-N… (More)
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2001
2001
PURPOSE To determine if mutations in ABCR (ABCA4) are associated with chloroquine/hydroxychloroquine retinopathy. METHODS DNA… (More)
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2000
Highly Cited
1998
Highly Cited
1998
Phosphorothioate oligodeoxynucleotides containing CpG (CpG-ODN) activate immune responses. We report that quinacrine, chloroquine… (More)
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1996
1996
We have synthesized several 4-aminoquinolines with shortened side chains that retain activity against chloroquine-resistant… (More)
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