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4-N-hydroxyethyl-2'-deoxycytosine methyl phosphate diester

Known as: HEDC methyl phosphodiester 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (2)

CytosineOrganophosphates
analogs & derivatives

Papers overview

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2010
2010
Nucleic Acids Research
The two helical parameters n and h where n is the number of nucleotide residues per turn and h is the height per nucleotide… 
2006
2006
Single-based resolution for oligodeoxynucleotides and their phosphorothioate modifications by replaceable capillary gel electrophoresis.
2003
2003
CpG oligonucleotides with modified termini and nicked dumbbell structure show enhanced immunostimulatory activity.
A series of 21 phosphodiester oligodeoxyribonucleotides containing the core sequence 5'-GACGTT-3' or related control sequences… 
2001
2001
2-Benzamidoethyl group--a novel type of phosphate protecting group for oligonucleotide synthesis.
A number of 5'-O-(4,4'-dimethoxytrityl)thymidine N,N-diisopropylamino phosphoramidites protected at P(III) with derivatives of 2… 
2000
2000
Towards the selection of phosphorothioate aptamers optimizing in vitro selection steps with phosphorothioate nucleotides.
The high affinity of a given nucleic acid for a protein ligand can be used to isolate specific inhibitors of enzymes involved in… 
1997
1997
Phosphodiester amidates of unsaturated nucleoside analogues: synthesis and anti-HIV activity.
The effect of introduction of a lipophilic phosphodiester amidate moiety on the HIV activity of inactive unsaturated nucleoside… 
1996
1996
Detailed characterization of antisense DNA oligonucleotides.
We have developed methods for verification of the structures of novel, chemically synthesized oligonucleotides having alternating… 
1996
1996
Cellular uptake and localization of liposomal-methylphosphonate oligodeoxynucleotides
Abstract Nuclease digestion and intracellular delivery are major factors limiting the potential use of oligodeoxynucleotides as… 
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