4,5-epoxymorphinan

 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1984-2018
0119842018

Papers overview

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2014
2014
The efflux transporter protein P-glycoprotein (P-gp) is capable of affecting the central distribution of diverse… (More)
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2008
2008
By focusing on 4,5-epoxymorphinan, a traditional opioid skeleton but a new structure in the opioid kappa-agonist research field… (More)
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2007
2007
An analog of nor-binaltorphimine (nor-BNI) without the 4,5-epoxy bridge, 17,17'-bis(cyclopropylmethyl)-6,6',7,7'-tetrahydro-6,6… (More)
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2006
2006
[reaction: see text]. A method was found for the novel synthesis of ortho ester derivatives that are potentially useful as… (More)
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2005
2005
Opioids, such as morphine, can directly alter immune function via receptors expressed on immunocompetent cells. However, several… (More)
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2004
2004
Morphine belongs to the class of compounds known as 4,5-epoxymorphinans, which can alter immune function directly via receptors… (More)
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2002
2002
Compounds of the 4,5-epoxymorphinan series have been shown to degrade in solution to the corresponding 2,2'-dimers when stored in… (More)
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1999
1999
TRK-820, a new type of 4,5-epoxymorphinan derivative, was investigated in vivo for antinociceptive activities and its selectivity… (More)
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1998
1998
A new type of kappa-agonist, 17-cyclopropylmethyl-3, 14 beta-dihydroxy-4,5 alpha-epoxy-6 beta-[N-methyl-trans-3-(3-furyl… (More)
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1992
1992
Thirteen 4,5-epoxymorphinan mu agonists with established analgesic action were docked into an Asp-Lys-His-Phe pseudoreceptor… (More)
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