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National Institutes of Health
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A Computational Model for Docking of Noncompetitive Neuraminidase Inhibitors and Probing their Binding Interactions with Neuraminidase of Influenza Virus H5N1.
Current computer-aided drug design
Corpus ID: 20499430
BACKGROUND With cases of emergence of drug resistance to the current competitive inhibitors of neuraminidase (NA) such as…
Identification through high‐throughput screening of 4'‐methoxyflavone and 3',4'‐dimethoxyflavone as novel neuroprotective inhibitors of parthanatos
British journal of pharmacology
Corpus ID: 22447544
The current lack of disease‐modifying therapeutics to manage neurological and neurodegenerative conditions justifies the…
Bioavailable Flavonoids: Cytochrome P450-Mediated Metabolism of Methoxyflavones
Drug Metabolism and Disposition
Corpus ID: 14127983
Methoxylated flavones were recently shown to be promising cancer chemopreventive agents. Their high metabolic stability compared…
Oxidation and rearrangements of flavanones by mammalian cytochrome P450
Xenobiotica; the fate of foreign compounds in…
Corpus ID: 40361511
To clarify the metabolic pathways of flavanones in mammals, the metabolism of (±)-flavanone and (±)-4′-methoxyflavanone by rat…
Modulation of luminol-dependent chemiluminescence of murine macrophages by flavone and its synthetic derivatives.
B. D. Cunningham
Corpus ID: 23873702
The effect of flavone (CAS 525-82-6, 2-phenylbenzopyran-4-one, 1), flavone-8-acetic acid (CSA 87626-55-9, FAA, 2) and 10…
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