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4'-hydroxywarfarin

Known as: 4-hydroxy-3-(1-(4-hydroxyphenyl)-3-oxobutyl)-2H-1-benzopyran-2-one 
National Institutes of Health

Papers overview

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2013
2013
Coumadin (R/S-warfarin) is a highly efficacious and widely used anticoagulant; however, its highly variable metabolism remains an… 
Highly Cited
1993
Highly Cited
1993
The regio- and stereoselectivity of warfarin metabolism have been used to assess structure-function relationships of human P4502C… 
1991
1991
Healthy men were administered i.v. racemic warfarin, S-warfarin or R-warfarin on two occasions, once in the drug-free state and… 
1989
1989
Warfarin, an anticoagulant and "metabolic probe" for cytochrome P-450 isozyme multiplicity, is metabolized to 4'-hydroxywarfarin… 
Highly Cited
1987
Highly Cited
1987
The mechanism of the drug interaction in humans between warfarin and rifampin was investigated by monitoring the elimination… 
1979
1979
Immunoassay techniques offer promise for the selective analysis of enantiomeric substances without prior separation. In a… 
Highly Cited
1970
Highly Cited
1970
Warfarin and its metabolites were excreted by the rat in urine (two-thirds of the dose) and feces (one-third of the dose). For… 
Highly Cited
1969
Highly Cited
1969
  • R. O'Reilly
  • Journal of Clinical Investigation
  • 1969
  • Corpus ID: 1529925
The interaction of the anticoagulant drug warfarin and its metabolites with human plasma albumin was studied by equilibrium…