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4'-hydroxyflurbiprofen

 
National Institutes of Health

Papers overview

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2010
2010
ABSTRACT The biotransformation of the fluorinated anti-inflammatory drug flurbiprofen was investigated in Cunninghamella spp… Expand
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2008
2008
The effects of genetic polymorphisms in drug-metabolizing enzymes (e.g., CYP2C9*3) on drug clearance have been well characterized… Expand
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2007
2007
AIMS We investigated flurbiprofen pharmacokinetics in 12 volunteers to develop a phenotypic trait measure that correlates with… Expand
2006
2006
We have previously shown that flurbiprofen metabolism to 4′‐hydroxyflurbiprofen provides an in vivo measure of cytochrome P450… Expand
2001
2001
Dapsone has been shown to activate flurbiprofen 4'-hydroxylation by expressed CYP2C9 enzyme and in human liver microsomes. It has… Expand
2000
2000
A high-performance liquid chromatographic assay has been developed for the simultaneous quantitation of flurbiprofen and its… Expand
Highly Cited
1993
Highly Cited
1993
Results of an on-line HPLC-NMR analysis of human urine from a volunteer administered the anti-inflammatory drug flurbiprofen are… Expand
1992
1992
1. The concentrations of the R- and S-enantiomers of flurbiprofen and its metabolites were measured in plasma and urine following… Expand
1990
1990
The effect of oral cimetidine or ranitidine on the pharmacokinetics of the R and S enantiomers of the nonsteroidal anti… Expand
1989
1989
Reversed-phase high-performance liquid chromatographic methods have been developed to quantitate the R- and S-enantiomers of… Expand