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3p21

A chromosome band present on 3p
National Institutes of Health

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12 relations
CCR1 wt AlleleCCR5 wt AlleleCCRL2 wt AlleleCDC25A wt Allele
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Papers overview

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Highly Cited
2013
Highly Cited
2013
Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis
BACKGROUND Findings from family and twin studies suggest that genetic contributions to psychiatric disorders do not in all cases… Expand
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Highly Cited
2013
Highly Cited
2013
Adverse Outcomes in Clear Cell Renal Cell Carcinoma with Mutations of 3p21 Epigenetic Regulators BAP1 and SETD2: A Report by MSKCC and the KIRC TCGA Research Network
Purpose: To investigate the impact of newly identified chromosome 3p21 epigenetic tumor suppressors PBRM1, SETD2, and BAP1 on… Expand
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Highly Cited
2007
Highly Cited
2007
Mutation in Glycerol-3-Phosphate Dehydrogenase 1–Like Gene (GPD1-L) Decreases Cardiac Na+ Current and Causes Inherited Arrhythmias
Background— Brugada syndrome is a rare, autosomal-dominant, male-predominant form of idiopathic ventricular fibrillation… Expand
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Highly Cited
2004
Highly Cited
2004
A Susceptibility Locus at Chromosome 3p21 Linked to Familial Nasopharyngeal Carcinoma
Nasopharyngeal carcinoma (NPC) poses one of the serious health problems in southern Chinese, with an incidence rate ranging from… Expand
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Highly Cited
2000
Highly Cited
2000
Epigenetic inactivation of a RAS association domain family protein from the lung tumour suppressor locus 3p21.3
Allelic loss at the short arm of chromosome 3 is one of the most common and earliest events in the pathogenesis of lung cancer… Expand
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Highly Cited
1996
Highly Cited
1996
Genetic Restriction of HIV-1 Infection and Progression to AIDS by a Deletion Allele of the CKR5 Structural Gene
The chemokine receptor 5 (CKR5) protein serves as a secondary receptor on CD4+ T lymphocytes for certain strains of human… Expand
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Highly Cited
1996
Highly Cited
1996
The FHIT Gene at 3p14.2 Is Abnormal in Lung Cancer
To determine the role of the FHIT gene, which encompasses the fragile site at 3p14.2, we analyzed 59 tumors of the small cell and… Expand
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Highly Cited
1995
Highly Cited
1995
SCN5A mutations associated with an inherited cardiac arrhythmia, long QT syndrome
Long QT syndrome (LQT) is an inherited disorder that causes sudden death from cardiac arrhythmias, specifically torsade de… Expand
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Highly Cited
1994
Highly Cited
1994
Mutation in the DNA mismatch repair gene homologue hMLH 1 is associated with hereditary non-polyposis colon cancer
THE human DNA mismatch repair gene homologue, hMSH2, on chromosome 2p is involved in hereditary non-polyposis colon cancer (HNPCC… Expand
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Highly Cited
1994
Highly Cited
1994
Mutation of a mutL homolog in hereditary colon cancer.
Some cases of hereditary nonpolyposis colorectal cancer (HNPCC) are due to alterations in a mutS-related mismatch repair gene. A… Expand
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