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30 nm Chromatin Fiber

Known as: 30 nm Fiber, Chromatin Fiber, Chromatin Fibril 
A level of DNA packaging in chromatin above that of the nucleosome, the fundamental subunit of chromatin structure. The chromatin fiber has a… Expand
National Institutes of Health

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Highly Cited
2015
Highly Cited
2015
Chromatin Fibers Are Formed by Heterogeneous Groups of Nucleosomes In Vivo
Nucleosomes help structure chromosomes by compacting DNA into fibers. To gain insight into how nucleosomes are arranged in vivo… Expand
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Highly Cited
2014
Highly Cited
2014
Cryo-EM Study of the Chromatin Fiber Reveals a Double Helix Twisted by Tetranucleosomal Units
Double Helix, Doubled Chromatin consists of genomic DNA packaged onto nucleosomes—double donut-shaped complexes of histone… Expand
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Highly Cited
2012
Highly Cited
2012
Chromosomes without a 30-nm chromatin fiber
How is a long strand of genomic DNA packaged into a mitotic chromosome or nucleus? The nucleosome fiber (beads-on-a-string), in… Expand
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Review
2010
Review
2010
HMGB proteins: interactions with DNA and chromatin.
HMGB proteins are members of the High Mobility Group (HMG) superfamily, possessing a unique DNA-binding domain, the HMG-box… Expand
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Highly Cited
2008
Highly Cited
2008
30 nm chromatin fibre decompaction requires both H4-K16 acetylation and linker histone eviction.
The mechanism by which chromatin is decondensed to permit access to DNA is largely unknown. Here, using a model nucleosome array… Expand
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Review
2007
Review
2007
Higher-Order Structures of Chromatin: The Elusive 30 nm Fiber
Despite progress in understanding chromatin function, the structure of the 30 nm chromatin fiber has remained elusive. However… Expand
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Highly Cited
2006
Highly Cited
2006
Histone H4-K16 Acetylation Controls Chromatin Structure and Protein Interactions
Acetylation of histone H4 on lysine 16 (H4-K16Ac) is a prevalent and reversible posttranslational chromatin modification in… Expand
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Highly Cited
2006
Highly Cited
2006
EM measurements define the dimensions of the "30-nm" chromatin fiber: evidence for a compact, interdigitated structure.
Chromatin structure plays a fundamental role in the regulation of nuclear processes such as DNA transcription, replication… Expand
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Highly Cited
2004
Highly Cited
2004
Chromatin Architecture of the Human Genome Gene-Rich Domains Are Enriched in Open Chromatin Fibers
We present an analysis of chromatin fiber structure across the human genome. Compact and open chromatin fiber structures were… Expand
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Highly Cited
2004
Highly Cited
2004
Nucleosome Arrays Reveal the Two-Start Organization of the Chromatin Fiber
Chromatin folding determines the accessibility of DNA constituting eukaryotic genomes and consequently is profoundly important in… Expand
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