FAQ

30 nm Chromatin Fiber

Known as: 30 nm Fiber, Chromatin Fiber, Chromatin Fibril 
A level of DNA packaging in chromatin above that of the nucleosome, the fundamental subunit of chromatin structure. The chromatin fiber has a… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1969-2017
010203019692017

Papers overview

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2012
2012
Chromosomes without a 30-nm chromatin fiber
How is a long strand of genomic DNA packaged into a mitotic chromosome or nucleus? The nucleosome fiber (beads-on-a-string), in… (More)
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Highly Cited
2009
Highly Cited
2009
Single-molecule force spectroscopy reveals a highly compliant helical folding for the 30-nm chromatin fiber
The compaction of eukaryotic DNA into chromatin has been implicated in the regulation of all DNA processes. To unravel the higher… (More)
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Highly Cited
2009
Highly Cited
2009
Evidence for heteromorphic chromatin fibers from analysis of nucleosome interactions.
The architecture of the chromatin fiber, which determines DNA accessibility for transcription and other template-directed… (More)
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Highly Cited
2008
Highly Cited
2008
30 nm chromatin fibre decompaction requires both H4-K16 acetylation and linker histone eviction.
The mechanism by which chromatin is decondensed to permit access to DNA is largely unknown. Here, using a model nucleosome array… (More)
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Highly Cited
2008
Highly Cited
2008
Nucleosome repeat length and linker histone stoichiometry determine chromatin fiber structure.
To understand how nuclear processes involving DNA are regulated, knowledge of the determinants of chromatin condensation is… (More)
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Highly Cited
2006
Highly Cited
2006
EM measurements define the dimensions of the "30-nm" chromatin fiber: evidence for a compact, interdigitated structure.
Chromatin structure plays a fundamental role in the regulation of nuclear processes such as DNA transcription, replication… (More)
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Highly Cited
2004
Highly Cited
2004
Chromatin Architecture of the Human Genome Gene-Rich Domains Are Enriched in Open Chromatin Fibers
We present an analysis of chromatin fiber structure across the human genome. Compact and open chromatin fiber structures were… (More)
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Highly Cited
2004
Highly Cited
2004
Nucleosome arrays reveal the two-start organization of the chromatin fiber.
Chromatin folding determines the accessibility of DNA constituting eukaryotic genomes and consequently is profoundly important in… (More)
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Highly Cited
2000
Highly Cited
2000
Pulling a single chromatin fiber reveals the forces that maintain its higher-order structure.
Single chicken erythrocyte chromatin fibers were stretched and released at room temperature with force-measuring laser tweezers… (More)
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1998
1998
Chromatin conformation in living cells: support for a zig-zag model of the 30 nm chromatin fiber.
A new method was used to probe the conformation of chromatin in living mammalian cells. The method employs ionizing radiation and… (More)
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