3-oxo-3-phenylpropyne

Known as: 1-phenyl-2-propyn-1-one

National Institutes of Health

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1984

1984

Chemical modification of hydroxynitrile lyase by selective reaction of an essential cysteine-SH group with alpha, beta-unsaturated propiophenones as pseudo-substrates.

3-Oxo-3-phenylpropyne and 3-oxo-3-phenylpropene were synthesized as active-site-directed irreversible inhibitors of the bitter…