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3-methyl-aminothiophene dicarboxylic acid
National Institutes of Health
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Prolonged Postinhibitory Rebound Firing in the Cerebellar Nuclei Mediated by Group I Metabotropic Glutamate Receptor Potentiation of L-Type Calcium Currents
I. M. Raman
The Journal of Neuroscience
Corpus ID: 22501386
Neurons in the cerebellar nuclei fire at accelerated rates for prolonged periods after trains of synaptic inhibition that…
Differential role of mGlu1 and mGlu5 receptors in rat hippocampal slice models of ischemic tolerance
The European journal of neuroscience
Corpus ID: 3177228
Activation of glutamate receptors has been proposed as a key factor in the induction of ischemic tolerance. We used organotypic…
Stereoselective synthesis and preliminary evaluation of (+)- and (-)-3-methyl-5-carboxy-thien-2-yl-glycine (3-MATIDA): identification of (+)-3-MATIDA as a novel mGluR1 competitive antagonist.
Corpus ID: 21376933
The synthesis of the (+)- and (-)-isomers of 3-methyl-5-carboxy-thyen-2-yl-glycine (3-MATIDA), heterocyle isosters of…
Metabotropic glutamate 1 (mGlu1) receptor antagonists enhance GABAergic neurotransmission: a mechanism for the attenuation of post-ischemic injury and epileptiform activity?
Corpus ID: 22126840
Selective antagonists of mGlu1 metabotropic glutamate receptors attenuate neuronal death in models of cerebral ischemia. Because…
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