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3-isopropylmalate dehydrogenase activity
Known as:
(2R,3S)-3-isopropylmalate:NAD+ oxidoreductase activity
, beta-IPM dehydrogenase activity
, IPMDH
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Catalysis of the reaction: 3-carboxy-2-hydroxy-4-methylpentanoate + NAD+ = 3-carboxy-4-methyl-2-oxopentanoate + NADH + H+. [EC:1.1.1.85]
National Institutes of Health
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Papers overview
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2018
2018
Novel Substrate Specificity of Designer 3-Isopropylmalate Derived from Thermus thermophiltts HB 8 Dehydrogenase
M. Fujita
,
TadashiEGucHI Hideyuki TAMEGAi
2018
Corpus ID: 4742031
Redesigning of an enzyme for a new catalytic reaction alld modified substrate specificity was exploited with 3isopropylmalate…
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2016
2016
Pressure adaptation of 3-isopropylmalate dehydrogenase from an extremely piezophilic bacterium is attributed to a single amino acid substitution
Y. Hamajima
,
T. Nagae
,
N. Watanabe
,
E. Ohmae
,
Y. Kato-Yamada
,
C. Kato
Extremophiles
2016
Corpus ID: 254077504
3-Isopropylmalate dehydrogenase (IPMDH) from the extreme piezophile Shewanella benthica (SbIPMDH) is more pressure-tolerant than…
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2014
2014
Structural study of the pressure adaptation of proteins from deep-sea bacteria
N. Watanabe
,
T. Nagae
,
Hiroyuki Yamada
,
Naoto Shimoaka
2014
Corpus ID: 102467617
In recent years, significant development in the high-pressure macromolecular crystallography (HPMX) using a diamond anvil cell…
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