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3-hydroxyisobutyrate dehydrogenase activity

Catalysis of the reaction: 3-hydroxy-2-methylpropanoate + NAD+ = 2-methyl-3-oxopropanoate + NADH + H+. [EC:]
National Institutes of Health

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3-Hydroxyisobutyric aciduria is a rare entity and affected individuals display a range of clinical manifestations including… Expand