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3-deazaneplanocin

Known as: 3-deaza-neplanocin 
 
National Institutes of Health

Papers overview

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2014
2014
Histone lysine methylation regulates gene expression and cancer initiation. Bioinformatics analysis suggested that DOT1L, a… Expand
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2013
2013
BACKGROUND & AIMS Enhancer of zeste homolog 2 (EZH2) is a histone methyltransferase that is overexpressed by pancreatic ductal… Expand
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2013
2013
BackgroundEmbryonal Rhabdomyosarcoma (RMS) is a pediatric soft-tissue sarcoma derived from myogenic precursors that is… Expand
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Highly Cited
2012
Highly Cited
2012
Epigenetic histone modifications are thought to underlie the rapid memory immune response to recall antigen that develops after… Expand
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2012
2012
Enhancer of zeste homologue 2 (EZH2) is the catalytic subunit of Polycomb repressive complex 2 that catalyzes the trimethylation… Expand
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Review
2011
Review
2011
Control of gene expression is exerted at a number of different levels, one of which is the accessibility of genes and their… Expand
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Highly Cited
2011
Highly Cited
2011
Latent HIV proviruses are silenced as the result of deacetylation and methylation of histones located at the viral long terminal… Expand
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2006
2006
Neplanocin F is a natural carbocyclic nucleoside. Herein, we describe the synthesis and antiviral activity of (+/-)-5'-deoxy… Expand
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Review
2001
Review
2001
Poxviruses continue to pose a major threat to human health. Monkeypox is endemic in central Africa, and the discontinuation of… Expand
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Highly Cited
1986
Highly Cited
1986
3-Deazaneplanocin, a new carbocyclic analog of adenosine, was synthesized as an inhibitor of S-adenosylhomocysteine hydrolase… Expand
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