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3-deazaadenosine

 
National Institutes of Health

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Highly Cited
2006
Highly Cited
2006
Chronic hyperhomocysteinemia (HHcy) is an important factor in development of arterial hypertension. HHcy is associated with… Expand
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Highly Cited
1995
Highly Cited
1995
3-Deazaadenosine (DZA), 3-deaza-(+/-)-aristeromycin (DZAri), and 3-deazaneplanocin A (DZNep) are powerful modulators of cellular… Expand
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1986
1986
The effects of 3-deazaaristeromycin and 3-deazaadenosine on RNA methylation and synthesis were examined in the mouse macrophage… Expand
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Highly Cited
1983
Highly Cited
1983
The carbocyclic analog of 3-deazaadenosine (C-c3 Ado) was found to inhibit in vitro the replication of several DNA and RNA… Expand
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Highly Cited
1982
Highly Cited
1982
The carbocyclic analogue of 3-deazaadenosine (3-deaza-C-Ado) has been synthesized and found to have antiviral activity in cell… Expand
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Highly Cited
1981
Highly Cited
1981
In the reaction adenosine + L-homocysteine = S-adenosyl-L-homocysteine, catalyzed by S-adenosylhomo-cysteine hydrolase from beef… Expand
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Highly Cited
1981
Highly Cited
1981
3-Deazaadenosine, an inhibitor of methylation, increased the frequency of conversion of 3T3-L1 fibroblasts to fat cells in a dose… Expand
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Highly Cited
1979
Highly Cited
1979
Elevated levels of adenosylmethionine (AdoMet) and adenosylhomocysteine (AdoHcy) were observed in livers of rats injected with 3… Expand
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Highly Cited
1978
Highly Cited
1978
3-Deazaadenosine (deazaAdo) inhibits lymphocyte-mediated cytolysis in vitro at micromolar concentrations and is potentiated… Expand
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Highly Cited
1978
Highly Cited
1978
Abstract 3-Deazaadenosine, a known potent inhibitor of adenosylhomocysteine hydrolase, exerts an inhibitory effect on the… Expand
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