3-bromo-2-ketoglutarate

Known as: Pentanedioic acid, 3-bromo-2-oxo-, (+-)-, bromoketoglutarate

National Institutes of Health

Papers overview

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1992

1992

Inactivation of pig heart NADP-specific isocitrate dehydrogenase by two affinity reagents is due to reaction with a cysteine not essential for function.

Gerald E. Smyth, Roberta F. Colman
Archives of biochemistry and biophysics
1992

Pig heart NADP-dependent isocitrate dehydrogenase is 65% inactivated by 3-bromo-2-ketoglutarate (Ehrlich, R.S., and Colman, R.F… (More)

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1989

1989

Cysteinyl peptide labeled by 3-bromo-2-ketoglutarate in the active site of pig heart NAD+-dependent isocitrate dehydrogenase.

Ashish Kumer Saha, Y. C. Huang, Roberta F. Colman
Biochemistry
1989

The substrate affinity label 3-bromo-2-ketoglutarate (BrKG) reacts covalently with pig heart NAD+-specific isocitrate… (More)

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1987

1987

Characterization of an active site peptide modified by the substrate analogue 3-bromo-2-ketoglutarate on a single chain of dimeric NADP+-dependent isocitrate dehydrogenase.

Reuben Ehrlich, Roberta F. Colman
The Journal of biological chemistry
1987

The substrate analogue 3-bromo-2-ketoglutarate reacts with pig heart NADP+-dependent isocitrate dehydrogenase to yield partially… (More)

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1984

1984

The role of dissimilar subunits of NAD-specific isocitrate dehydrogenase from pig heart. Evaluation using affinity labeling.

Reuben Ehrlich, Roberta F. Colman
The Journal of biological chemistry
1984

NAD-specific isocitrate dehydrogenase from pig heart is composed of three dissimilar subunits present in the native enzyme as 2… (More)

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1982

1982

3-Bromo-2-ketoglutarate: a substrate and affinity label for diphosphopyridine nucleotide dependent isocitrate dehydrogenase.

Renate Bednar, Fred C. Hartman, Roberta F. Colman
Biochemistry
1982

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1982

1982

Chemical modification A probe of the structure and function of the subunits of DPN-dependent isocitrate dehydrogenase.

Renate Bednar, Roberta F. Colman
The Journal of biological chemistry
1982

DPN-dependent isocitrate dehydrogenase is composed of three distinct types of subunits: alpha, beta, and gamma which have… (More)

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1981

1981

Interaction of isocitrate dehydrogenase with (RS)-3-bromo-2-ketoglutarate. A potential affinity label for alpha-ketoglutarate binding sites.

Fred C. Hartman
Biochemistry
1981

The interaction of oxidized nicotine adenine dinucleotide phosphate dependent isocitrate dehydrogenase (from pig heart) with (RS… (More)

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