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3-alpha-hydroxycholanate dehydrogenase activity

Known as: 3alpha-hydroxy-5beta-cholanate:NAD+ oxidoreductase activity, 3alpha-hydroxycholanate dehydrogenase activity, alpha-hydroxy-cholanate dehydrogenase activity 
Catalysis of the reaction: lithocholate + NAD(+) = 3-oxo-5beta-cholanate + H(+) + NADH. [EC:1.1.1.52, RHEA:19588]
National Institutes of Health

Papers overview

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2014
2014
THE EFFECT OF BILE ACID SALT SODIUM 3ALPHA, 7ALPHA-DIHYDROXY-12-KETO-5BETA-CHOLANATE (MKC) AND PROBIOTIC PRETREATMENT ON GLICLAZIDE PERMEATION IN ILEAL TISSUES FROM HEALTHY AND DIABETIC RATS
2009
2009
Cefotaxime pharmacokinetics after oral application in the form of 3alpha,7alpha-dihydroxy-12-keto-5beta-cholanate microvesicles in rat.
The aim of ths study was to investigate the pharmacokinetics of cefotaxime sodium (CEF) pharmacokinetics after oral application… 
2008
2008
The influence of 3alpha,7alpha-dihydroxy-12-keto-5beta-cholanate on gliclazide pharmacokinetics and glucose levels in a rat model of diabetes.
The aim of this study was to investigate the pharmacokinetics and glucose-lowering activity of gliclazide alone and in… 
2007
2007
Radiation doses from some [3H]-labelled organic compounds following ingestion.
Published information, especially human data, on the biokinetics of 11 compounds labelled with 3H was used to develop simple… 
2004
2004
3Alpha,7alpha-dihydroxy-12-oxo-5beta-cholanate as blood-brain barrier permeator.
The aim of the study was to test the efficacy of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanate as a blood-brain barrier (BBB… 
1981
1981
5beta-cholestane-3alpha, 27-diol: NAD+ oxidoreductase and 3alpha-hydroxy-5beta-cholestan-27-al; NAD+ oxidoreductase in rat liver extract.
1977
1977
3alpha-hydroxy-5beta-cholest-24-ene compounds and methods for their preparation
1975
1975
Synthetic studies of withanolides. Part I. Synthesis of 5,6beta-epoxy-4beta-hydroxy-5beta-cholest-2-en-1-one and related compounds.
The title compounds, which have functionalities in rings A and B similar to those of withaferin A(1), have been synthesized… 
1974
1974
Bile acids. XL. Methyl 3beta, 7beta-dihydroxy-5alpha-cholanate. An example of dehydrogenation with Raney nickel.
1952
1952
Preparation of Chenodeoxycholic Acid from Cholic Acid
KAWAI1 converted cholic acid to chenodeoxycholic acid (3α : 7α-dihydroxycholanic acid, anthropodeoxycholic acid) by Kishner–Wolff… 
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