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3-alpha-Hydroxysteroid Dehydrogenase (B-Specific)

Known as: 3alpha-Hydroxysteroid Dehydrogenase (B-specific), 3-alpha-Hydroxysteroid Dehydrogenase (B-Specific) [Chemical/Ingredient], 3 alpha-Hydroxysteroid Dehydrogenase (B-Specific) 
A 3-hydroxysteroid dehydrogenase which catalyzes the reversible reduction of the active androgen, DIHYDROTESTOSTERONE to 5 ALPHA-ANDROSTANE-3 ALPHA… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1958-2012
05101519582012

Related topics

Related topics

11 relations

Narrower (1)

5 alpha-Dihydroprogesterone 3 alpha-Hydroxysteroid Oxidoreductase
DHRS9 geneDHRS9 protein, humanIn BloodProcess of secretion
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Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
3-alpha-Hydroxysteroid Dehydrogenase (B-Specific)
physiological aspects
In Blood
chemical synthesis
standards characteristics
Process of secretion

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2004
2004
Anatomical and cellular localization of neuroactive 5 alpha/3 alpha-reduced steroid-synthesizing enzymes in the spinal cord.
The complementary activities of 5 alpha-reductase (5 alpha-R) and 3 alpha-hydroxysteroid dehydrogenase (3 alpha-HSD) are crucial… (More)
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2003
2003
Selective reduction of AKR1C2 in prostate cancer and its role in DHT metabolism.
BACKGROUND As androgens play an essential role in prostate cancer, we sought to develop a real-time PCR to characterize mRNA… (More)
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2002
2002
Kinetics of allopregnanolone formation catalyzed by human 3 alpha-hydroxysteroid dehydrogenase type III (AKR1C2).
Allopregnanolone is a neurosteroid which exhibits anxiolytic and anticonvulsant activities through potentiation of the GABA(A… (More)
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1997
1997
Expression and characterization of recombinant type 2 3 alpha-hydroxysteroid dehydrogenase (HSD) from human prostate: demonstration of bifunctional 3 alpha/17 beta-HSD activity and cellular…
In androgen target tissues, 3alpha-hydroxysteroid dehydrogenase (3alpha-HSD) may regulate occupancy of the androgen receptor (AR… (More)
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1996
1996
Characterization of a 3 alpha-hydroxysteroid dehydrogenase/carbonyl reductase from the gram-negative bacterium Comamonas testosteroni.
A new form of the NAD(P)-dependent 3 alpha-hydroxysteroid dehydrogenases (3 alpha-HSDs), present in the gram-negative bacterium… (More)
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Highly Cited
1996
Highly Cited
1996
Down-regulation of expression and function of the rat liver Na+/bile acid cotransporter in extrahepatic cholestasis.
BACKGROUND & AIMS The molecular regulation of hepatic bile acid transporters during cholestasis is largely unknown. Cloning of… (More)
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Highly Cited
1996
Highly Cited
1996
5 alpha-reduced androgens play a key role in murine parturition.
Two steroid 5 alpha-reductase isozymes designated type 1 and 2 synthesize 5 alpha-reduced androgens and other 5 alpha-reduced… (More)
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1995
1995
Substrate specificity, gene structure, and tissue-specific distribution of multiple human 3 alpha-hydroxysteroid dehydrogenases.
We have expressed in Escherichia coli functionally active proteins encoded by two human cDNAs that were isolated previously by… (More)
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1993
1993
Differential localization of the 5 alpha-reductase and the 3 alpha-hydroxysteroid dehydrogenase in neuronal and glial cultures.
The activities of the 5 alpha-reductase [the enzyme that converts testosterone into dihydrotestosterone (DHT)] and 3 alpha… (More)
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1981
1981
Reduction of zearalenone to zearalenol in female rat liver by 3 alpha-hydroxysteroid dehydrogenase.
The distribution of the zearalenone reducing activity was investigated in liver fractions obtained by differential centrifugation… (More)
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