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3-alpha-Hydroxysteroid Dehydrogenase (B-Specific)

Known as: 3alpha-Hydroxysteroid Dehydrogenase (B-specific), 3-alpha-Hydroxysteroid Dehydrogenase (B-Specific) [Chemical/Ingredient], 3 alpha-Hydroxysteroid Dehydrogenase (B-Specific) 
A 3-hydroxysteroid dehydrogenase which catalyzes the reversible reduction of the active androgen, DIHYDROTESTOSTERONE to 5 ALPHA-ANDROSTANE-3 ALPHA… Expand
National Institutes of Health

Related topics

Related topics

11 relations

Narrower (1)

5 alpha-Dihydroprogesterone 3 alpha-Hydroxysteroid Oxidoreductase
DHRS9 geneDHRS9 protein, humanIn BloodProcess of secretion
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2001
Review
2001
Minireview: 11β-Hydroxysteroid Dehydrogenase Type 1- A Tissue-Specific Amplifier of Glucocorticoid Action.
11β-hydroxysteroid dehydrogenases (11β-HSDs) catalyze the interconversion of active glucocorticoids (cortisol, corticosterone… Expand
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Highly Cited
1998
Highly Cited
1998
Mutagenesis of 3 alpha-hydroxysteroid dehydrogenase reveals a "push-pull" mechanism for proton transfer in aldo-keto reductases.
Rat liver 3 alpha-hydroxysteroid dehydrogenase (3 alpha-HSD, E.C. 1.1.1.213, AKR1C9) is a member of the aldo-keto reductase (AKR… Expand
Highly Cited
1996
Highly Cited
1996
Down-regulation of expression and function of the rat liver Na+/bile acid cotransporter in extrahepatic cholestasis.
BACKGROUND & AIMS The molecular regulation of hepatic bile acid transporters during cholestasis is largely unknown. Cloning of… Expand
Highly Cited
1996
Highly Cited
1996
5 alpha-reduced androgens play a key role in murine parturition.
Two steroid 5 alpha-reductase isozymes designated type 1 and 2 synthesize 5 alpha-reduced androgens and other 5 alpha-reduced… Expand
Highly Cited
1995
Highly Cited
1995
Substrate Specificity, Gene Structure, and Tissue-specific Distribution of Multiple Human 3α-Hydroxysteroid Dehydrogenases (*)
We have expressed in Escherichia coli functionally active proteins encoded by two human cDNAs that were isolated previously by… Expand
Highly Cited
1993
Highly Cited
1993
Differential localization of the 5 alpha-reductase and the 3 alpha-hydroxysteroid dehydrogenase in neuronal and glial cultures.
The activities of the 5 alpha-reductase [the enzyme that converts testosterone into dihydrotestosterone (DHT)] and 3 alpha… Expand
Review
1993
Review
1993
Androgen and progesterone metabolism in the central and peripheral nervous system
This paper summarizes the most recent data obtained in the authors' laboratory on the metabolism of testosterone and progesterone… Expand
Highly Cited
1991
Highly Cited
1991
Cloning and sequencing of the cDNA for rat liver 3 alpha-hydroxysteroid/dihydrodiol dehydrogenase.
Rat liver 3 alpha-hydroxysteroid dehydrogenase (3 alpha-HSD, EC 1.1.1.50) is an NAD(P)(+)-dependent oxidoreductase which will… Expand
Highly Cited
1981
Highly Cited
1981
Direct spectrophotometry of total bile acids in serum.
In this simple and direct method for determining total bile acids in serum, the serum was mixed with sodium pyruvate, a lactate… Expand
Review
1978
Review
1978
Re-evaluation of the 3 alpha-hydroxysteroid dehydrogenase assay for total bile acids in bile.
A review of the 3 alpha-hydroxysteroid dehydrogenase method for determining the concentration of total bile acids in bile is… Expand
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