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3,7-dimethyl-1-propargylxanthine

Known as: DMPX 
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
Adenosinergic systems have been implicated in anxiety-like states, as caffeine can induce a state of anxiety in human beings… Expand
Highly Cited
2002
Highly Cited
2002
Under normoxic conditions, macrophages from C57BL mice produce low levels of vascular endothelial growth factor (VEGF). Hypoxia… Expand
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Highly Cited
2001
Highly Cited
2001
Recent epidemiological studies have established an association between the common consumption of coffee or other caffeinated… Expand
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Highly Cited
1999
Highly Cited
1999
The objective of this study was to characterize the behavior induced by the N-methyl-D-aspartate receptor antagonist MK-801… Expand
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Highly Cited
1997
Highly Cited
1997
A series of 8-substituted derivatives of 3,7-dimethyl-1-propargylxanthine (DMPX) was synthesized and investigated as A2A… Expand
Highly Cited
1996
Highly Cited
1996
Adenosine agonists inhibit TNF-alpha production in macrophage and monocytes, but the mechanism is unknown. Therefore, we studied… Expand
Highly Cited
1995
Highly Cited
1995
1 Purine analogues have been examined for anxiolytic‐ and anxiogenic‐like activity in mice, by use of the elevated plus‐maze. 2… Expand
Highly Cited
1993
Highly Cited
1993
Methotrexate, a folate antagonist, is a potent antiinflammatory agent when used weekly in low concentrations. We examined the… Expand
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Highly Cited
1992
Highly Cited
1992
The A2 adenosine receptor agonist, CGS 21680 in nanomolar concentrations, reversibly increased in a concentration-dependent… Expand
Highly Cited
1988
Highly Cited
1988
3,7-Dimethyl-1-propargylxanthine (DMPX), a caffeine analog that exhibits in vitro selectivity for A2-adenosine receptors… Expand