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3,4-dihydroxyphenylglycolaldehyde

 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1986-2007
01219862007

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Aldehydes

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
3,4-dihydroxyphenylglycolaldehyde
Aldehydes

Papers overview

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2008
2008
Neurotoxic catecholamine metabolite in nociceptors contributes to painful peripheral neuropathy.
The neurotoxic effects of catecholamine metabolites have been implicated in neurodegenerative diseases. As some sensory neurons… (More)
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Review
2007
Review
2007
Neurotoxicity and metabolism of the catecholamine-derived 3,4-dihydroxyphenylacetaldehyde and 3,4-dihydroxyphenylglycolaldehyde: the role of aldehyde dehydrogenase.
Aldehydes are highly reactive molecules formed during the biotransformation of numerous endogenous and exogenous compounds… (More)
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Review
2004
Review
2004
Neurotoxicity of MAO metabolites of catecholamine neurotransmitters: role in neurodegenerative diseases.
The monoamine oxidase (MAO) metabolites of norepinephrine (NE) or epinephrine (EPI) and of dopamine (DA) are 3,4… (More)
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2003
2003
Convenient syntheses of biogenic aldehydes, 3,4-dihydroxyphenylacetaldehyde and 3,4-dihydroxyphenylglycolaldehyde.
The title compounds were prepared from a common precursor, a bis-THP-protected dihydroxyphenylacetic acid methyl ester. Key steps… (More)
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2001
2001
3,4-Dihydroxyphenylacetaldehyde and hydrogen peroxide generate a hydroxyl radical: possible role in Parkinson's disease pathogenesis.
3,4-Dihydroxyphenylacetaldehyde (DOPAL) and 3,4-dihydroxyphenylglycolaldehyde (DOPEGAL), the monoamine oxidase (MAO) metabolites… (More)
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2001
2001
Catecholamine monoamine oxidase a metabolite in adrenergic neurons is cytotoxic in vivo.
3,4-Dihydroxyphenylglycolaldehyde is the monoamine oxidase-A metabolite of two catecholamine neurotransmitters, epinephrine and… (More)
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1999
1999
Accumulation of 3,4-dihydroxyphenylglycolaldehyde, the neurotoxic monoamine oxidase A metabolite of norepinephrine, in locus ceruleus cell bodies in Alzheimer's disease: mechanism of neuron death.
3,4-Dihydroxyphenylglycolaldehyde (DOPEGAL) is the neurotoxic monoamine oxidase A (MAO-A) metabolite of norepinephrine (NE). NE… (More)
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1999
1999
Quantitation of 3,4-dihydroxyphenylacetaldehyde and 3, 4-dihydroxyphenylglycolaldehyde, the monoamine oxidase metabolites of dopamine and noradrenaline, in human tissues by microcolumn high…
We recently described the chemical synthesis of 3, 4-dihydroxyphenylacetaldehyde and 3,4-dihydroxyphenylglycolaldehyde, the… (More)
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1989
1989
Detection of 3,4-dihydroxyphenylglycolaldehyde in human brain by high-performance liquid chromatography.
The monoamine oxidase A metabolite of noradrenaline, 3,4-dihydroxyphenylglycolaldehyde, is the precursor of 3,4-dihydroxymandelic… (More)
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1986
1986
Human aldehyde dehydrogenase: kinetic identification of the isozyme for which biogenic aldehydes and acetaldehyde compete.
Michaelis constants and maximal velocities for phenylacetaldehyde (a metabolite of phenylethylamine), 3,4… (More)
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