3,4-dihydroxyphenylacetaldehyde

Known as: DHPAA aldehyde 
 
National Institutes of Health

Papers overview

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2017
2017
BACKGROUND The aldehyde metabolite of dopamine, 3,4-dihydroxyphenylacetaldehyde (DOPAL) is an endogenous neurotoxin implicated in… (More)
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2015
2015
Oxidative deamination of dopamine produces the highly toxic aldehyde 3,4-dihydroxyphenylacetaldehyde (DOPAL), enhanced production… (More)
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2011
2011
The oxidation and toxicity of dopamine is believed to contribute to the selective neurodegeneration associated with Parkinson… (More)
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2009
2009
Dopamine (DA) has been implicated as an endogenous neurotoxin to explain selective neurodegeneration, as observed for Parkinson's… (More)
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Review
2009
Review
2009
Persistent inflammation and the generation of reactive oxygen and nitrogen species play pivotal roles in tissue injury during… (More)
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Review
2007
Review
2007
Aldehydes are highly reactive molecules formed during the biotransformation of numerous endogenous and exogenous compounds… (More)
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2004
2004
This work was carried out in order to evaluate the in vitro and in vivo toxicity of 3,4-dihydroxyphenylacetaldehyde (DOPAL). This… (More)
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Highly Cited
2003
Highly Cited
2003
In Parkinson's disease (PD), there is a highly selective loss of dopamine (DA) neurons in the substantia nigra (SN) greater than… (More)
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2000
2000
3,4-Dihydroxyphenylacetaldehyde (DOPAL) has been reported to be a toxic metabolite formed by the oxidative-deamination of… (More)
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1978
1978
It was demonstrated that DOPAL, the aldehyde derived from the action of MAO on dopamine, can condense with dopamine to form THP… (More)
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