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3,4-dihydroxyphenylacetaldehyde

Known as: DHPAA aldehyde 
 
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
Parkinson's disease entails profound loss of nigrostriatal dopaminergic terminals, decreased vesicular uptake of intraneuronal… Expand
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Highly Cited
2011
Highly Cited
2011
The oxidation and toxicity of dopamine is believed to contribute to the selective neurodegeneration associated with Parkinson… Expand
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Highly Cited
2009
Highly Cited
2009
Dopamine (DA) has been implicated as an endogenous neurotoxin to explain selective neurodegeneration, as observed for Parkinson's… Expand
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Highly Cited
2007
Highly Cited
2007
Recent evidence indicates a role for oxidative stress and resulting products, e.g. 4-hydroxy-2-nonenal (4HNE) in the pathogenesis… Expand
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Highly Cited
2003
Highly Cited
2003
In Parkinson's disease (PD), there is a highly selective loss of dopamine (DA) neurons in the substantia nigra (SN) greater than… Expand
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Highly Cited
2001
Highly Cited
2001
Parkinson's disease (PD) is a major cause of age-related morbidity and mortality, present in nearly 1% of individuals at ages 70… Expand
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Highly Cited
2001
Highly Cited
2001
3,4-Dihydroxyphenylacetaldehyde (DOPAL) and 3,4-dihydroxyphenylglycolaldehyde (DOPEGAL), the monoamine oxidase (MAO) metabolites… Expand
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Highly Cited
2000
Highly Cited
2000
3,4‐Dihydroxyphenylacetaldehyde (DOPAL) has been reported to be a toxic metabolite formed by the oxidative‐deamination of… Expand
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Highly Cited
2000
Highly Cited
2000
3,4-Dihydroxyphenylacetaldehyde (DOPAL) is a toxic metabolite formed by the oxidative deamination of dopamine. This aldehyde is… Expand
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Highly Cited
1981
Highly Cited
1981
Abstract In the presence of ethanol, the metabolism of dopamine in rat liver slices is altered such that the major product is 3,4… Expand
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